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Palladium-catalyzed aerobic oxidative cyclization of N-aryl imines: indole synthesis from anilines and ketones.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Wei, Ye Deb, Indubhusan Yoshikai, Naohiko |
| Copyright Year | 2012 |
| Abstract | We report here an operationally simple, palladium-catalyzed cyclization reaction of N-aryl imines, affording indoles via the oxidative linkage of two C-H bonds under mild conditions using molecular oxygen as the sole oxidant. The process allows quick and atom-economical assembly of indole rings from inexpensive and readily available anilines and ketones and tolerates a broad range of functional groups. |
| Starting Page | 735 |
| Ending Page | 736 |
| Page Count | 2 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.lac.dicp.ac.cn/tswz/yzhsh8.pdf |
| PubMed reference number | 22612535v1 |
| Alternate Webpage(s) | https://doi.org/10.1021/ja3030824 |
| DOI | 10.1021/ja3030824 |
| Journal | Journal of the American Chemical Society |
| Volume Number | 134 |
| Issue Number | 22 |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Aniline Compounds Aryl Hydrocarbon Hydroxylases Cyclization Imines Indoles Ketone Measurement Oxidants Oxygen Palladium Ring device arylsulfatase activity genetic linkage indole biosynthetic process |
| Content Type | Text |
| Resource Type | Article |