Loading...
Please wait, while we are loading the content...
Denitrogenative palladium-catalyzed coupling of aryl halides with arylhydrazines under mild conditions.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Chang, Sheng Dong, Lin Lin Song, Hai Qing Feng, Bo |
| Copyright Year | 2018 |
| Abstract | The development of a method for the Pd(ii)-catalyzed denitrogenative coupling of arylhydrazines to give functionalized biaryls in good yield, using aryl bromides or aryl iodides as convenient and inexpensive aryl sources, is reported. High functional group tolerance is demonstrated for electronically distinct arylhydrazines as well as aryl halides. The desired products were isolated in good to excellent yields for 58 examples. Control experiments and mechanism studies revealed that the transformation undergoes a base-promoted Pd-catalyzed process. |
| Starting Page | 3282 |
| Ending Page | 3288 |
| Page Count | 7 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.rsc.org/suppdata/c8/ob/c8ob00305j/c8ob00305j1.pdf |
| PubMed reference number | 29666872v1 |
| Alternate Webpage(s) | https://doi.org/10.1039/c8ob00305j |
| DOI | 10.1039/c8ob00305j |
| Journal | Organic & biomolecular chemistry |
| Volume Number | 16 |
| Issue Number | 17 |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Aryl Hydrocarbon Hydroxylases Bromides Iodides Palladium arylsulfatase activity |
| Content Type | Text |
| Resource Type | Article |