NDLI: Human T-cell leukemia virus (HTLV-I) antibodies in Africa.

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Human T-cell leukemia virus (HTLV-I) antibodies in Africa.

Content Provider	Semantic Scholar
Author	Saxinger, W. Carl Blattner, William A. Levine, Paul H. Clark, J. V. Biggar, Robert John Hoh, M. W. Moghissi, J. Jacobs, Paul Wilson, Louise Jacobson, R. A.
Copyright Year	1984
Abstract	Antibodies specific for human T-cell leukemia-lymphoma virus type I (HTLV-I) were demonstrated in serum samples from various groups of people in South Africa, Uganda, Ghana, Nigeria, Tunisia, and Egypt. The samples had been collected for other purposes and were presumably selected without bias toward clinical conditions associated with HTLV infections. Regional differences in antibody positivity were observed, indicating widely distributed loci of occurrence of HTLV on the African continent in people of both black and white ancestry. Two patients with high titers of antibody to HTLV-I had some signs of adult T-cell leukemia-lymphoma. In several groups a high frequency of false positive serum reactions was indicated when specific confirmation steps were included in the assay. Further characterization of these sera revealed highly elevated immunoglobulin levels, possibly due to polyclonal activation of immunoglobulin synthesis in these subjects. The possibility that related cross-reactive human retroviruses coexist in the same groups was not eliminated.
Starting Page	59
Ending Page	66
Page Count	8
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://www.epiinformatics.com/ADPublications/UniqueHIV.pdf
PubMed reference number	6089348v1
Volume Number	225
Issue Number	4669
Journal	Science
Language	English
Access Restriction	Open
Subject Keyword	Adult T-Cell Lymphoma/Leukemia Cellular Phone Chronic Lymphocytic Leukemia Cross Reactions HIV Infections Leukemia, B-Cell Lymphoma Patients Retroviridae T-Cell Leukemia Viruses, Human confirmation - ResponseLevel
Content Type	Text
Resource Type	Article

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