NDLI: Whole-Body Fluorescence Imaging in Cancer Research

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Whole-Body Fluorescence Imaging in Cancer Research

Content Provider	Scilit
Author	Shirmanova, Marina V. Yuzhakova, Diana V. Lukina, Maria M. Gavrina, Alena I. Meleshina, Aleksandra V. Turchin, Ilya V. Zagaynova, Elena V.
Copyright Year	2020
Description	This chapter provides an overview of the major applications of fluorescence whole-body imaging in living mice with a focus on cancer studies. Fluorescence whole-body imaging of small animals is a powerful in vivo technology with many biomedical applications, among which cancer research occupies a central position. The use of time-resolved techniques allows registration of both the fluorescence intensity and the fluorescence lifetime. Potential agents for chemotherapy, one of the major treatment approaches for most cancers, can also be characterized in vivo using fluorescence assessments. because most therapeutic molecules are nonfluorescent, labeling with a fluorophore is required to visualize their localization within the whole mouse body. The relationships between photosensitizer photobleaching and the photodynamic therapy responses have been investigated in vivo for many photosensitizers. Continuous visual monitoring of tumor growth and spread within intact animals became possible by the use of fluorescent proteins of the green fluorescent protein family. Book Name: Imaging from Cells to Animals In Vivo
Related Links	https://content.taylorfrancis.com/books/download?dac=C2016-0-43082-9&isbn=9781315174662&doi=10.1201/9781315174662-24&format=pdf
Ending Page	336
Page Count	12
Starting Page	325
DOI	10.1201/9781315174662-24
Language	English
Publisher	Informa UK Limited
Publisher Date	2020-12-03
Access Restriction	Open
Subject Keyword	Book Name: Imaging From Cells To Animals In Vivo Biomedical Engineering Treatment Proteins Animals Cancer Research Photosensitizers Body Fluorescence Imaging Fluorescence Whole Body
Content Type	Text
Resource Type	Chapter

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