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Effect of Aging on the Activities of Acetylcholinesterase, Na+, K+-ATPase and Mg2+-ATPase in Rat Pituitary and Hypothalamus
| Content Provider | Scilit |
|---|---|
| Author | Tsakiris, Stylianos Angelogianni, Panagoula Stavridis, John C. |
| Copyright Year | 1998 |
| Abstract | Acetylcholinesterase (AChE), Na+, K+-ATPase and Mg2+-ATPase activities were estimated in homogenised rat pituitary and hypothalamus of 4-and 22-month-old rats. AChE activity was not altered in the pituitary of aged com pared to adult rats, while it was found decreased by about 40% in the hypothalamus. Na+,K+-ATPase activity remained stable in the hypothalamus, while it was decreased by about 38% in the pituitary. Mg2+-ATPase activity remained unchanged in the hypothalamus, but was increased by about 83% in the pituitary. This pituitary Na+, K+-ATPase inactivation may result in pathological mood and decreased neural excitability and metabolic energy production in aged animals.The age-related alterations of AChE , Na+, K+-ATPase and Mg2+-ATPase activities may reflect changes in secretion and responses of some hormones of pituitary and hypothalamus. |
| Related Links | http://www.degruyter.com/downloadpdf/j/znc.1998.53.issue-3-4/znc-1998-3-405/znc-1998-3-405.xml |
| Ending Page | 172 |
| Page Count | 5 |
| Starting Page | 168 |
| e-ISSN | 18657125 |
| DOI | 10.1515/znc-1998-3-405 |
| Journal | Zeitschrift für Naturforschung C |
| Issue Number | 3-4 |
| Volume Number | 53 |
| Language | English |
| Publisher | Walter de Gruyter GmbH |
| Publisher Date | 1998-04-01 |
| Access Restriction | Open |
| Subject Keyword | Zeitschrift Für Naturforschung C Gerontology Aging Rat Pituitary Rat Hypothalamus Acetylcholinesterase Na+ K+-atpase Mg2+-atpase Journal: Zeitschrift für Naturforschung C, Vol- 53 |
| Content Type | Text |
| Resource Type | Article |
