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Anti–miR-148a regulates platelet FcγRIIA signaling and decreases thrombosis in vivo in mice
| Content Provider | Scilit |
|---|---|
| Author | Zhou, Yuhang Abraham, Shaji Andre, Pierrette Edelstein, Leonard C. Shaw, Chad A. Dangelmaier, Carol A. Tsygankov, Alexander Y. Kunapuli, Satya P. Bray, Paul F. McKenzie, Steven E. |
| Copyright Year | 2015 |
| Description | Key Points TULA-2 negatively regulates platelet FcγRIIA signaling by dephosphorylating Syk. miR-148a targets TULA-2 and inhibition of miR-148a decreases FcγRIIA-mediated platelet activation and thrombosis in vivo. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692146/pdf |
| Ending Page | 2881 |
| Page Count | 11 |
| Starting Page | 2871 |
| DOI | 10.1182/blood-2015-02-631135 |
| Journal | Blood |
| Issue Number | 26 |
| Volume Number | 126 |
| Language | English |
| Publisher | American Society of Hematology |
| Publisher Date | 2015-12-24 |
| Access Restriction | Open |
| Subject Keyword | Research and Experimental Medicine Syk Mir 148a Dephosphorylating Fcγriia Signaling Regulates Platelet Fcγriia Journal: Blood (Vol- 2018, Issue- 26) |
| Content Type | Text |
| Resource Type | Article |