NDLI: CK2β regulates thrombopoiesis and Ca2+-triggered platelet activation in arterial thrombosis

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CK2β regulates thrombopoiesis and Ca2+-triggered platelet activation in arterial thrombosis

Content Provider	Scilit
Author	Münzer, Patrick Walker-Allgaier, Britta Geue, Sascha Langhauser, Friederike Geuss, Eva Stegner, David Aurbach, Katja Semeniak, Daniela Chatterjee, Madhumita Menendez, Irene Gonzalez Märklin, Melanie Quintanilla-Martinez, Leticia Salih, Helmut R. Litchfield, David W. Buchou, Thierry Kleinschnitz, Christoph Lang, Florian Nieswandt, Bernhard Pleines, Irina Schulze, Harald Gawaz, Meinrad Borst, Oliver
Copyright Year	2017
Description	Key Points CK2β is critically required for thrombopoiesis by regulating tubulin polymerization, MK fragmentation, and proplatelet formation. CK2β facilitates inositol triphosphate–mediated increase of cytosolic Ca2+ and is essential for platelet activation in arterial thrombosis in vivo.
Related Links	https://ashpublications.org/blood/article-pdf/130/25/2774/1404396/blood784413.pdf
Ending Page	2785
Page Count	12
Starting Page	2774
DOI	10.1182/blood-2017-05-784413
Journal	Blood
Issue Number	25
Volume Number	130
Language	English
Publisher	American Society of Hematology
Publisher Date	2017-12-21
Access Restriction	Open
Subject Keyword	Research and Experimental Medicine Ca2 Regulates Thrombopoiesis Platelet Activation in Arterial Thrombosis Journal: Blood (Vol- 2013, Issue- 25)
Content Type	Text
Resource Type	Article

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