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Soft Matter Vol - 8 Issue - 5

Synthesis of sodium alginate based sprayable new soft gel system

Content Provider	Royal Society of Chemistry (RSC)
Author	Siddhanta, A. K. Prasad, Kamalesh Chhatbar, Mahesh U. Chejara, Dharmesh R.
Copyright Year	2012
Abstract	Chemical reaction of sodium alginate (Na-Alg) with o-aminobenzoic acid (OABA) and m-aminobenzoic acid (MABA) in the presence of 1-ethyl-3-[3-(dimethylamino)propyl]-carbodiimide hydrochloride (EDC) afforded amide derivatives capable of forming viscous hydrogel systems exhibiting thixotropic behaviour. Characterization of the amide materials was done by employing FT-IR and 13C NMR, wherein amide formation between Na-Alg and OABA or MABA was confirmed. The thixotropic behaviour was evaluated by rheology and viscometry showing superior thixotropicity of OABA based amide to its MABA counterpart. The characteristic of the soft gel turning into a flowing liquid on gentle stirring predisposes it for possible application as a delivery system or sprayable gel material for transporting small active molecules to the targeted locations in health and personal care formulations.
Starting Page	1837
Ending Page	1844
Page Count	8
File Format	HTM / HTML PDF
ISSN	1744683X
Volume Number	8
Issue Number	6
Journal	Soft Matter
DOI	10.1039/c2sm06947d
Language	English
Publisher	Royal Society of Chemistry
Access Restriction	Open
Subject Keyword	Thixotropy EDC Rheology Alginic acid Carbodiimide Fourier-transform infrared spectroscopy Gel MABA Chemical reaction OABA Carboxylic acid Amide Viscometer Nuclear magnetic resonance Maba language
Content Type	Text
Resource Type	Article
Subject	Chemistry Condensed Matter Physics

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