NDLI: DNA-modified graphene quantum dots as a sensing platform for detection of Hg<sup>2+</sup> in living cells

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DNA-modified graphene quantum dots as a sensing platform for detection of Hg²⁺ in living cells

Content Provider	Royal Society of Chemistry (RSC)
Author	Zhao, Huimin Tan, Feng Zhao, Xin Cong, Longchao Li, Xiaoyu He, Xin Gao, Jinsuo
Copyright Year	2015
Abstract	Detection of metal ions in living cells is significant in environmental monitoring and health risk assessment. This paper reports a simple and facile method for the detection of Hg2+ ions in Hela cells through fluorescence imaging, which was based on the fluorescence quenching in thymine-rich DNA modified graphene quantum dots (DNA-GQDs) in the presence of Hg2+. The decrease in the fluorescence intensity was attributed to the electron transfer of DNA-GQDs due to Hg2+ bound to the thymine bases of the DNA, resulting in a T–T mismatch hairpin structure. The method shows high selectivity and sensitivity. This present sensing platform will have broad applications in biological imaging and environmental monitoring.
Starting Page	39587
Ending Page	39591
Page Count	5
File Format	HTM / HTML PDF
ISSN	20462069
Volume Number	5
Issue Number	49
Journal	RSC Advances
DOI	10.1039/c5ra06984j
Language	English
Publisher	Royal Society of Chemistry
Access Restriction	Open
Subject Keyword	Hela Hela Province Graphene DNA Thymine Fluorescence Quantum information science
Content Type	Text
Resource Type	Article
Subject	Chemistry Chemical Engineering

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