NDLI: Water-soluble jack-knife prawn extract inhibits 5-hydroxytryptamine-induced vasoconstriction and platelet aggregation in humans

Please wait, while we are loading the content...

Quercetin and its metabolites inhibit the membrane NADPH oxidase activity in vascular smooth muscle cells from normotensive and spontaneously hypertensive rats

Dietary fucoidan of Acaudina molpadioides and its enzymatically degraded fragments could prevent intestinal mucositis induced by chemotherapy in mice

Solubilization by freeze-milling of water-insoluble subunits in rice proteins

Isolation and identification of ingredients inducing cancer cell death from the seeds of Alpinia galanga, a Chinese spice

Water-soluble jack-knife prawn extract inhibits 5-hydroxytryptamine-induced vasoconstriction and platelet aggregation in humans

Lutein derived fragments exhibit higher antioxidant and anti-inflammatory properties than lutein in lipopolysaccharide induced inflammation in rats

Curcumin improves high glucose-induced INS-1 cell insulin resistance via activation of insulin signaling

Effects of compound Ginkgo biloba on intestinal permeability in rats with alcohol-induced liver injury

Chronic caffeine treatment enhances the resilience to social defeat stress in mice

Beneficial effects of soy milk and fiber on high cholesterol diet-induced alteration of gut microbiota and inflammatory gene expression in rats

Lowering of cholesterol bioaccessibility and serum concentrations by saponins: in vitro and in vivo studies

Differential protective effects of polyphenol extracts from apple peels and fleshes against acute CCl₄-induced liver damage in mice

In vitro assessment of the prebiotic potential of Aloe vera mucilage and its impact on the human microbiota

Relating the effects of protein type and content in increased-protein cheese pies to consumers’ perception of satiating capacity

Anti-apoptotic and anti-glycative effects of asiatic acid in the brain of d-galactose treated mice

Mitochondrial reactive oxygen species production mediates ursolic acid-induced mitochondrial uncoupling and glutathione redox cycling, with protection against oxidant injury in H9c2 cells

Lactobacillus rhamnosus LA68 and Lactobacillus plantarum WCFS1 differently influence metabolic and immunological parameters in high fat diet-induced hypercholesterolemia and hepatic steatosis

Rice bran protein hydrolysates prevented interleukin-6- and high glucose-induced insulin resistance in HepG2 cells

Carbonyl trapping and antiglycative activities of olive oil mill wastewater

Inhibitory effect of leonurine on the formation of advanced glycation end products

The effect of low or high molecular weight oat beta-glucans on the inflammatory and oxidative stress status in the colon of rats with LPS-induced enteritis

Gentio-oligosaccharides from Leuconostoc mesenteroides NRRL B-1426 dextransucrase as prebiotics and as a supplement for functional foods with anti-cancer properties

The anti-inflammatory potential of a moderately hydrolysed casein and its 5 kDa fraction in in vitro and ex vivo models of the gastrointestinal tract

Enrichment of ACE inhibitory peptides in navy bean (Phaseolus vulgaris) using lactic acid bacteria

Cholesterol side chain analogs but not its ether analogs possess cholesterol-lowering activity

Antrodan, A β-glucan obtained from Antrodia cinnamomea mycelia, is beneficial to benign prostate hyperplasia

Back cover

Food & Function Vol -5

Food & Function Vol -4

Food & Function Vol -3

Food & Function Vol -2

Food & Function Vol -1

Water-soluble jack-knife prawn extract inhibits 5-hydroxytryptamine-induced vasoconstriction and platelet aggregation in humans

Content Provider	Royal Society of Chemistry (RSC)
Author	Ohkura, Masamichi Nakamura, Eisaku Hayashi, Masahiro Fujimoto, Shouichi Kanai, Tasuku Gamoh, Shuji Yamasaki, Tetsuo Tanaka-Totoribe, Naoko Yamamoto, Ryuichi Yokota, Atsuko Watanabe, Akiko Kuwabara, Masachika
Copyright Year	2015
Abstract	Coronary artery spasm plays an important role in the pathogenesis of various ischemic heart diseases or serious arrhythmia. The aim of this study is to look for functional foods which have physiologically active substances preventing 5-hydroxytryptamine (5-HT)-related vasospastic diseases including peri- and postoperative ischemic complications of coronary artery bypass grafting (CABG) from ocean resources in Japanese coastal waters. First, we evaluated the effect of water-soluble ocean resource extracts on the response to 5-HT in HEK293 cells which have forcibly expressed cyan fluorescent protein-fused 5-HT2A receptors (5-HT2A-CFP). Among 5 different water-soluble extracts of ocean resources, the crude water-soluble jack-knife prawn extract (WJPE) significantly reduced maximal Ca2+ influx induced by 0.1 μM 5-HT in a concentration-dependent manner. The Crude WJPE significantly inhibited, in a concentration-dependent manner, 5-HT-induced constriction of human saphenous vein. 5-HT released from activated platelets plays a crucial roles in the constriction of coronary artery. Next the WJPE was purified for applying the experiment of 5-HT-induced human platelet aggregation. The purified WJPE significantly inhibited 5-HT-induced human platelet aggregation also in a concentration-dependent manner. Based on our findings, jack-knife prawn could be one of a functional food with health-promoting benefits for most people with vasospastic diseases including patients who have gone CABG.
Starting Page	444
Ending Page	449
Page Count	6
File Format	HTM / HTML PDF
ISSN	20426496
Volume Number	6
Issue Number	2
Journal	Food & Function
DOI	10.1039/c4fo00716f
Language	English
Publisher	Royal Society of Chemistry
Access Restriction	Open
Subject Keyword	Vasospasm Ischemia Cardiac arrhythmia Coronary circulation Skin grafting Cyan 5-HT2A receptor Pocketknife Prawn Great saphenous vein Platelet Functional food
Content Type	Text
Resource Type	Article
Subject	Medicine Food Science

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Contractions to 5-hydroxytryptamine in human coronary artery and human saphenous vein.

Relative Contributions of 5-Hydroxytryptamine (5-HT) Receptor Subtypes in 5-HT-Induced Vasoconstriction of the Distended Human Saphenous Vein as a Coronary Artery Bypass Graft

Low-dose aspirin inhibits platelet-induced contraction of the human isolated coronary artery. A role for additional 5-hydroxytryptamine receptor antagonism against coronary vasospasm?

Increased Contractile Function of Human Saphenous Vein Grafts Harvested by “No-Touch” Technique

Improving coronary artery bypass graft durability: use of the external saphenous vein graft support

Angiotensin II, as well as 5-hydroxytriptamine, is a potent vasospasm inducer of saphenous vein graft for coronary artery bypass grafting in patients with diabetes mellitus

Relative contributions of 5-hydroxytryptamine (5-HT) receptor subtypes in 5-HT-induced vasoconstriction of the distended human saphenous vein as a coronary artery bypass graft.

An examination of 5-hydroxytryptamine receptors in human saphenous vein

“Extended length” endoscopic harvest of the great saphenous vein for coronary artery bypass grafting

Water-soluble jack-knife prawn extract inhibits 5-hydroxytryptamine-induced vasoconstriction and platelet aggregation in humans

Similar Documents

Contractions to 5-hydroxytryptamine in human coronary artery and human saphenous vein.

Relative Contributions of 5-Hydroxytryptamine (5-HT) Receptor Subtypes in 5-HT-Induced Vasoconstriction of the Distended Human Saphenous Vein as a Coronary Artery Bypass Graft

Low-dose aspirin inhibits platelet-induced contraction of the human isolated coronary artery. A role for additional 5-hydroxytryptamine receptor antagonism against coronary vasospasm?

Increased Contractile Function of Human Saphenous Vein Grafts Harvested by “No-Touch” Technique

Improving coronary artery bypass graft durability: use of the external saphenous vein graft support

Angiotensin II, as well as 5-hydroxytriptamine, is a potent vasospasm inducer of saphenous vein graft for coronary artery bypass grafting in patients with diabetes mellitus

Relative contributions of 5-hydroxytryptamine (5-HT) receptor subtypes in 5-HT-induced vasoconstriction of the distended human saphenous vein as a coronary artery bypass graft.

An examination of 5-hydroxytryptamine receptors in human saphenous vein

“Extended length” endoscopic harvest of the great saphenous vein for coronary artery bypass grafting

Water-soluble jack-knife prawn extract inhibits 5-hydroxytryptamine-induced vasoconstriction and platelet aggregation in humans