NDLI: <i>Lactobacillus plantarum</i> NCU116 attenuates cyclophosphamide-induced intestinal mucosal injury, metabolism and intestinal microbiota disorders in mice

Please wait, while we are loading the content...

Ceratonia siliqua L. hydroethanolic extract obtained by ultrasonication: antioxidant activity, phenolic compounds profile and effects in yogurts functionalized with their free and microencapsulated forms

Resveratrol modulates intestinal morphology and HSP70/90, NF-κB and EGF expression in the jejunal mucosa of black-boned chickens on exposure to circular heat stress

Effects of waxy rice starch and short chain amylose (SCA) on the formation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in a model system

Postprandial dietary fatty acids exert divergent inflammatory responses in retinal-pigmented epithelium cells

Bioaccessibility of provitamin A carotenoids from fruits: application of a standardised static in vitro digestion method

Intactness of cell wall structure controls the in vitro digestion of starch in legumes

Standardized extract of Tinospora crispa stimulates innate and adaptive immune responses in Balb/c mice

Redox chemistry of the molecular interactions between tea catechins and human serum proteins under simulated hyperglycemic conditions

Formation of reactive aldehydes (MDA, HHE, HNE) during the digestion of cod liver oil: comparison of human and porcine in vitro digestion models

The difference between oats and beta-glucan extract intake in the management of HbA1c, fasting glucose and insulin sensitivity: a meta-analysis of randomized controlled trials

Protective effects of rice dreg protein hydrolysates against hydrogen peroxide-induced oxidative stress in HepG-2 cells

Intake of bean sprouts influences melatonin and antioxidant capacity biomarker levels in rats

Breakdown pathways during oral processing of different breads: impact of crumb and crust structures

Bioactivity, proximate, mineral and volatile profiles along the flowering stages of Opuntia microdasys (Lehm.): defining potential applications

Fish oil diet modulates epididymal and inguinal adipocyte metabolism in mice

Bioavailability, rheology and sensory evaluation of fat-free yogurt enriched with VD₃ encapsulated in re-assembled casein micelles

Fast hepatic biotransformation of p-synephrine and p-octopamine and implications for their oral intake

Protective effects of Chaenomeles thibetica extract against carbon tetrachloride-induced damage via the MAPK/Nrf2 pathway

Plant polyphenols alter a pathway of energy metabolism by inhibiting fecal Bacteroidetes and Firmicutes in vitro

Antioxidant activity of a Lachnum YM226 melanin–iron complex and its influence on cytokine production in mice with iron deficiency anemia

Effects of boiling and in vitro gastrointestinal digestion on the antioxidant activity of Sonchus oleraceus leaves

Tartary buckwheat flavonoids protect hepatic cells against high glucose-induced oxidative stress and insulin resistance via MAPK signaling pathways

Adjuvant properties of water extractable arabinoxylans with different structural features from wheat flour against model antigen ovalbumin

Grape pomace and grape pomace extract improve insulin signaling in high-fat-fructose fed rat-induced metabolic syndrome

White adipose tissue urea cycle activity is not affected by one-month treatment with a hyperlipidic diet in female rats

Antibacterial activity of isolated phenolic compounds from cranberry (Vaccinium macrocarpon) against Escherichia coli

Ellagic acid inhibits non-enzymatic glycation and prevents proteinuria in diabetic rats

Lactobacillus plantarum NCU116 attenuates cyclophosphamide-induced intestinal mucosal injury, metabolism and intestinal microbiota disorders in mice

Structural analysis and immunostimulatory activity of glycopeptides from Paecilomyces sinensis

Supplementation of xylitol-containing chewing gum with probiotics: a double blind, randomised pilot study focusing on saliva flow and saliva properties

Hypoglycemic and anti-inflammatory effects of seabuckthorn seed protein in diabetic ICR mice

Pleurotus nebrodensis polysaccharide(PN50G) evokes A549 cell apoptosis by the ROS/AMPK/PI3K/AKT/mTOR pathway to suppress tumor growth

Vitamin E suppresses ex vivo osteoclastogenesis in ovariectomized rats

Antioxidant activity and nutrient release from polyphenol-enriched cheese in a simulated gastrointestinal environment

An investigation of process contaminants’ formation during the deep frying of breadcrumbs using a bread coat model

Grape skin phenolics as inhibitors of mammalian α-glucosidase and α-amylase – effect of food matrix and processing on efficacy

Antistaphylococcal activity and metabolite profiling of manuka honey (Leptospermum scoparium L.) after in vitro simulated digestion

Compounds from Caesalpinia sappan with anti-inflammatory properties in macrophages and chondrocytes

Involvement of miR-539-5p in the inhibition of de novo lipogenesis induced by resveratrol in white adipose tissue

Characterization of the antioxidant fraction of Trapa japonica pericarp and its hepatic protective effects in vitro and in vivo

Understanding of human metabolic pathways of different sub-classes of phenols from Arbutus unedo fruit after an acute intake

Correction: In vitro analysis of partially hydrolyzed guar gum fermentation differences between six individuals

Back cover

Food & Function Vol - 7 Issue - 2

Food & Function Vol -6

Food & Function Vol -5

Food & Function Vol -4

Food & Function Vol -3

Food & Function Vol -2

Food & Function Vol -1

Lactobacillus plantarum NCU116 attenuates cyclophosphamide-induced intestinal mucosal injury, metabolism and intestinal microbiota disorders in mice

Content Provider	Royal Society of Chemistry (RSC)
Author	Fan, Song-Tao Gong, Deming Xiong, Tao Xie, Jun-Hua Nie, Shao-Ping Yu, Qiang Xie, Ming-Yong
Copyright Year	2016
Abstract	Anticancer drugs at high doses often damage the intestinal mucosa and metabolism. Lactobacillus plantarum NCU116 (NCU116) isolated from pickled vegetables was orally given to cyclophosphamide-treated mice to determine its effects on intestinal mucosal injury, nutrient metabolism and colon microbiota, and investigate the mechanisms accounting for its effects. Mice treated with the bacterium were found to favorably recover intestine morphology of villus height and crypt depth, and have improved mucins expression and quantity of goblet cells, as well as intestinal metabolism by increasing the level of short-chain fatty acids and reducing the concentration of ammonia in the colon feces. In addition, NCU116-treated mice showed a higher diversity of colonic microbiota than the group without bacterium supplementation. The number of Lactobacillus and Bifidobacterium in the mouse colon was increased after bacterium intake, which decreased the number of potentially pathogenic bacteria, Escherichia coli and Pseudomonas. These results indicated that NCU116 could be of significant advantage in reducing intestinal mucosal injury and improving the intestinal metabolism and the intestinal microbiota.
Starting Page	1584
Ending Page	1592
Page Count	9
File Format	HTM / HTML PDF
ISSN	20426496
Volume Number	7
Issue Number	3
Journal	Food & Function
DOI	10.1039/c5fo01516b
Language	English
Publisher	Royal Society of Chemistry
Access Restriction	Open
Subject Keyword	Escherichia coli Pseudomonas Lactobacillus Gastrointestinal tract Metabolism Lactobacillus plantarum Pickling Large intestine Microbiota Intestinal gland Chalice Ammonia Gut flora Bifidobacterium Mouse
Content Type	Text
Resource Type	Article
Subject	Medicine Food Science

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Lactobacillus plantarum KLDS1.0318 Ameliorates Impaired Intestinal Immunity and Metabolic Disorders in Cyclophosphamide-Treated Mice

The effect of sun-dried raisins (Vitis vinifera L.) on the in vitro composition of the gut microbiota

Korean ginseng modulates the ileal microbiota and mucin gene expression in the growing rat

INDIGENOUS, NORMAL, AND AUTOCHTHONOUS FLORA OF THE GASTROINTESTINAL TRACT

Lactiplantibacillus plantarum Y42 in Biofilm and Planktonic States Improves Intestinal Barrier Integrity and Modulates Gut Microbiota of Balb/c Mice

Lactobacillus plantarum BSGP201683 Isolated from Giant Panda Feces Attenuated Inflammation and Improved Gut Microflora in Mice Challenged with Enterotoxigenic Escherichia coli

Bifidobacterium longum, Lactobacillus plantarum and Pediococcus acidilactici Reversed ETEC-Inducing Intestinal Inflammation in Mice.

Red wine polyphenols modulate fecal microbiota and reduce markers of the metabolic syndrome in obese patients

Lactobacillus plantarum PFM 105 Promotes Intestinal Development Through Modulation of Gut Microbiota in Weaning Piglets

Lactobacillus plantarum NCU116 attenuates cyclophosphamide-induced intestinal mucosal injury, metabolism and intestinal microbiota disorders in mice

Similar Documents

Lactobacillus plantarum KLDS1.0318 Ameliorates Impaired Intestinal Immunity and Metabolic Disorders in Cyclophosphamide-Treated Mice

The effect of sun-dried raisins (Vitis vinifera L.) on the in vitro composition of the gut microbiota

Korean ginseng modulates the ileal microbiota and mucin gene expression in the growing rat

INDIGENOUS, NORMAL, AND AUTOCHTHONOUS FLORA OF THE GASTROINTESTINAL TRACT

Lactiplantibacillus plantarum Y42 in Biofilm and Planktonic States Improves Intestinal Barrier Integrity and Modulates Gut Microbiota of Balb/c Mice

Lactobacillus plantarum BSGP201683 Isolated from Giant Panda Feces Attenuated Inflammation and Improved Gut Microflora in Mice Challenged with Enterotoxigenic Escherichia coli

Bifidobacterium longum, Lactobacillus plantarum and Pediococcus acidilactici Reversed ETEC-Inducing Intestinal Inflammation in Mice.

Red wine polyphenols modulate fecal microbiota and reduce markers of the metabolic syndrome in obese patients

Lactobacillus plantarum PFM 105 Promotes Intestinal Development Through Modulation of Gut Microbiota in Weaning Piglets

Lactobacillus plantarum NCU116 attenuates cyclophosphamide-induced intestinal mucosal injury, metabolism and intestinal microbiota disorders in mice