NDLI: Green tea extract improves the oxidative state of the liver and brain in rats with adjuvant-induced arthritis

Please wait, while we are loading the content...

Designing excipient emulsions to increase nutraceutical bioavailability: emulsifier type influences curcumin stability and bioaccessibility by altering gastrointestinal fate

Pomegranate extract induces ellagitannin metabolite formation and changes stool microbiota in healthy volunteers

Modulation of tissue fatty acids by l-carnitine attenuates metabolic syndrome in diet-induced obese rats

RNA sequencing supports distinct reactive oxygen species-mediated pathways of apoptosis by high and low size mass fractions of Bay leaf (Lauris nobilis) in HT-29 cells

Rice protein hydrolysates stimulate GLP-1 secretion, reduce GLP-1 degradation, and lower the glycemic response in rats

Induction of the superoxide anion radical scavenging capacity of dried ‘funori’Gloiopeltis furcata by Lactobacillus plantarum S-SU1 fermentation

The hypoglycemic effect of a polysaccharide (GLP) from Gracilaria lemaneiformis and its degradation products in diabetic mice

Inhibitory effects of wild bitter melon leaf extract on Propionibacterium acnes-induced skin inflammation in mice and cytokine production in vitro

Impact of bread making on fructan chain integrity and effect of fructan enriched breads on breath hydrogen, satiety, energy intake, PYY and ghrelin

Wild jujube polysaccharides protect against experimental inflammatory bowel disease by enabling enhanced intestinal barrier function

Caffeine ameliorates high energy diet-induced hepatic steatosis: sirtuin 3 acts as a bridge in the lipid metabolism pathway

Effects of thonningianin A in natural foods on apoptosis and cell cycle arrest of HepG-2 human hepatocellular carcinoma cells

Antioxidant and antiproliferative activities of polysaccharide fractions from litchi pulp

Supercritical fluid extraction of grape seeds: extract chemical composition, antioxidant activity and inhibition of nitrite production in LPS-stimulated Raw 264.7 cells

d-Fagomine attenuates metabolic alterations induced by a high-energy-dense diet in rats

Solid-state fermentation of whole oats to yield a synbiotic food rich in lactic acid bacteria and prebiotics

The protective role of the Bowman-Birk protease inhibitor in soybean lunasin digestion: the effect of released peptides on colon cancer growth

Amphiphilic zein hydrolysate as a novel nano-delivery vehicle for curcumin

Seasonal variations in the regiodistribution of oil extracted from small-spotted catshark and bogue

Lentinula edodes-derived polysaccharide rejuvenates mice in terms of immune responses and gut microbiota

Tartary buckwheat on nitric oxide-induced inflammation in RAW264.7 macrophage cells

Melatonin increases intracellular calcium in the liver, muscle, white adipose tissues and pancreas of diabetic obese rats

The ex vivo antiplatelet activation potential of fruit phenolic metabolite hippuric acid

Rehmannia glutinosa reduced waist circumferences of Korean obese women possibly through modulation of gut microbiota

Evaluation of anti-diabetic and alpha glucosidase inhibitory action of anthraquinones from Rheum emodi

Green tea extract improves the oxidative state of the liver and brain in rats with adjuvant-induced arthritis

Deciphering the binding patterns and conformation changes upon the bovine serum albumin–rosmarinic acid complex

Yeast with bacteriocin from ruminal bacteria enhances glucose utilization, reduces ectopic fat accumulation, and alters cecal microbiota in dietary-induced obese mice

A comparison of antioxidative and anti-inflammatory activities of sword beans and soybeans fermented with Bacillus subtilis

A novel Alaska pollack-derived peptide, which increases glucose uptake in skeletal muscle cells, lowers the blood glucose level in diabetic mice

Metabolic faecal fingerprinting of trans-resveratrol and quercetin following a high-fat sucrose dietary model using liquid chromatography coupled to high-resolution mass spectrometry

Development of a low fat fresh pork sausage based on chitosan with health claims: impact on the quality, functionality and shelf-life

Effect of 5-caffeoylquinic acid on the NF-κB signaling pathway, peroxisome proliferator-activated receptor gamma 2, and macrophage infiltration in high-fat diet-fed Sprague–Dawley rat adipose tissue

The effect of five Taraxacum species on in vitro and in vivo antioxidant and antiproliferative activity

Two Ganoderma species: profiling of phenolic compounds by HPLC–DAD, antioxidant, antimicrobial and inhibitory activities on key enzymes linked to diabetes mellitus, Alzheimer's disease and skin disorders

Gastroprotective potential against indomethacin and safety assessment of the homology of medicine and food formula cuttlebone complex

Activation of Nrf2 target enzymes conferring protection against oxidative stress in PC12 cells by ginger principal constituent 6-shogaol

Kaempferol suppresses lipid accumulation by inhibiting early adipogenesis in 3T3-L1 cells and zebrafish

Structural characterization and immunomodulatory effects of polysaccharides from Phellinus linteus and Phellinus igniarius on the IL-6/IL-10 cytokine balance of the mouse macrophage cell lines (RAW 264.7)

Acetic acid in aged vinegar affects molecular targets for thrombus disease management

Promising new applications of Castanea sativa shell: nutritional composition, antioxidant activity, amino acids and vitamin E profile

Correction: Chemopreventive activity of ellagitannins and their derivatives from black raspberry seeds on HT-29 colon cancer cells

Correction: Sulforaphane protected the injury of human vascular endothelial cell induced by LPC through up-regulating endogenous antioxidants and phase II enzymes

Back cover

Food & Function Vol - 6 Issue - 7

Food & Function Vol - 6 Issue - 6

Food & Function Vol - 6 Issue - 5

Food & Function Vol - 6 Issue - 4

Food & Function Vol - 6 Issue - 3

Food & Function Vol - 6 Issue - 2

Food & Function Vol -5

Food & Function Vol -4

Food & Function Vol -3

Food & Function Vol -2

Food & Function Vol -1

Green tea extract improves the oxidative state of the liver and brain in rats with adjuvant-induced arthritis

Content Provider	Royal Society of Chemistry (RSC)
Author	Gonçalves, Geferson de Almeida Sá-Nakanishi, Anacharis Babeto de Peralta, Rosane Marina Comar, Jurandir Fernando Amado, Ciomar Aparecida Bersani Wendt, Mariana Marques Nogueira Bracht, Adelar
Copyright Year	2015
Abstract	The purpose of the study was to evaluate the possible effects of the administration of a green tea extract on the oxidative state of the liver and brain of adjuvant-induced arthritic rats, a model for human rheumatoid arthritis. Daily doses of 250 mg kg−1 (59.8 mg catechins per kg) for 23 days were administered. This treatment produced significant diminutions in protein and lipid damage in liver, brain and plasma. It also diminished the tissue ROS contents and increased the antioxidant capacity of the plasma. The antioxidant defenses, which are diminished by arthritis, were improved by the green tea treatment, as revealed by the restoration of the GSH and protein thiol levels and by the strong tendency for normalizing the activities of the antioxidant enzymes. The activity of glucose 6-phosphate dehydrogenase, which is increased by arthritis in the liver, was also almost normalized by the treatment. In conclusion, it can be said that green tea consumption is possibly beneficial for the liver and brain of patients suffering from rheumatoid arthritis because it attenuates the pronounced oxidative stress that accompanies the disease and, thus, diminishes the injury to lipids and proteins in both liver and brain. There are also indications that, in the liver, the green tea can contribute to normalize the metabolic functions that are substantially modified by arthritis. For example, the green tea normalized the activity of glucose 6-phosphate dehydrogenase, a key enzyme of an important metabolic route (pentose monophosphate pathway). It is expected that the green tea treatment is equally able to normalize the activity of other enzymes (e.g., glucokinase and glucose 6-phosphatase), a hypothesis to be tested by future work.
Starting Page	2701
Ending Page	2711
Page Count	11
File Format	HTM / HTML PDF
ISSN	20426496
Volume Number	6
Issue Number	8
Journal	Food & Function
DOI	10.1039/c5fo00548e
Language	English
Publisher	Royal Society of Chemistry
Access Restriction	Open
Subject Keyword	Green tea Liver Rheumatoid arthritis Protein Lipid Blood plasma Reactive oxygen species Antioxidant Thiol Glucose 6-phosphate Oxidative stress Enzyme Pentose Glucokinase Glucose 6-phosphatase
Content Type	Text
Resource Type	Article
Subject	Medicine Food Science

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Green tea extract protects endothelial progenitor cells from oxidative insult through reduction of intracellular reactive oxygen species activity

Green tea extract protects endothelial progenitor cells from oxidative insult through reduction of intracellular reactive oxygen species activity.

Effect of green tea extract and vitamin C on oxidant or antioxidant status of rheumatoid arthritis rat model.

Targeting the pentose phosphate pathway in syndrome X-related cardiovascular complications

Influence of Chloramphenicol and Amoxicillin on Rat Liver Microsomal Enzymes and Lipid Peroxidation

Glucose-6-phosphate dehydrogenase protects escherichia coli from tellurite-mediated oxidative stress (2011).

Oxidative stress in erythrocytes from patients with rheumatoid arthritis

Effect of green tea extract and vitamin C on oxidant or antioxidant status of rheumatoid arthritis rat model

Changes in some liver enzymes in streptozotocin-induced diabetic rats fed sapogenin extract from bitter yam (dioscorea polygonoides) or commercial diosgenin.

Green tea extract improves the oxidative state of the liver and brain in rats with adjuvant-induced arthritis

Similar Documents

Green tea extract protects endothelial progenitor cells from oxidative insult through reduction of intracellular reactive oxygen species activity

Green tea extract protects endothelial progenitor cells from oxidative insult through reduction of intracellular reactive oxygen species activity.

Effect of green tea extract and vitamin C on oxidant or antioxidant status of rheumatoid arthritis rat model.

Targeting the pentose phosphate pathway in syndrome X-related cardiovascular complications

Influence of Chloramphenicol and Amoxicillin on Rat Liver Microsomal Enzymes and Lipid Peroxidation

Glucose-6-phosphate dehydrogenase protects escherichia coli from tellurite-mediated oxidative stress (2011).

Oxidative stress in erythrocytes from patients with rheumatoid arthritis

Effect of green tea extract and vitamin C on oxidant or antioxidant status of rheumatoid arthritis rat model

Changes in some liver enzymes in streptozotocin-induced diabetic rats fed sapogenin extract from bitter yam (dioscorea polygonoides) or commercial diosgenin.

Green tea extract improves the oxidative state of the liver and brain in rats with adjuvant-induced arthritis