NDLI: The effect of five Taraxacum species on in vitro and in vivo antioxidant and antiproliferative activity

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The effect of five Taraxacum species on in vitro and in vivo antioxidant and antiproliferative activity

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Food & Function Vol - 6 Issue - 7

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The effect of five Taraxacum species on in vitro and in vivo antioxidant and antiproliferative activity

Content Provider	Royal Society of Chemistry (RSC)
Author	Galán, A. Vicente, J. A. Mingarro, D. Muñoz Plaza, A. Acero, N. Martínez, M. P.
Copyright Year	2015
Abstract	Plants belonging to the genus Taraxacum are considered a nutritious food, being consumed raw or cooked. Additionally, these plants have long been used in folk medicine due to their choleretic, diuretic, antitumor, antioxidant, antiinflammatory, and hepatoprotective properties. This genus, with its complex taxonomy, includes several species that are difficult to distinguish. Its traditional use must be related not only to T. officinale F.H. Wigg., the most studied species, but also to others. The aim of this work is to compare five different common South European species of Taraxacum (T. obovatum (Willd.) DC., T. marginellum H. Lindb., T. hispanicum H. Lindb., T. lambinonii Soest and T. lacistrum Sahlin), in order to find differences between antioxidant and cytotoxic activities among them. Dissimilarities between species in LC/MS patterns, in in vitro and intracellular antioxidant activity and also in the cytotoxicity assay were found. T. marginellum was the most efficient extract reducing intracellular ROS levels although in in vitro assays, T. obovatum was the best free radical scavenger. A relevant cytotoxic effect was found in T. lacistrum extract over HeLa and HepG2 cell lines.
Starting Page	2787
Ending Page	2793
Page Count	7
File Format	HTM / HTML PDF
ISSN	20426496
Volume Number	6
Issue Number	8
Journal	Food & Function
DOI	10.1039/c5fo00645g
Language	English
Publisher	Royal Society of Chemistry
Access Restriction	Open
Subject Keyword	HeLa Willd Soest lacistrum Sahlin Genus Taraxacum Traditional medicine Choleretic Diuretic Antioxidant Anti-inflammatory Hepatoprotection Taraxacum officinale Carl Ludwig Willdenow Sextus Otto Lindberg Cytotoxicity Reactive oxygen species Scavenger (chemistry)
Content Type	Text
Resource Type	Article
Subject	Medicine Food Science

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