NDLI: Measurement of Scleral Thickness in Humans Using Anterior Segment Optical Coherent Tomography

Content Provider	PubMed Central
Author	Buckhurst, Hetal D. Gilmartin, Bernard Cubbidge, Robert P. Logan, Nicola S.
Editor	Paul, Friedemann
Copyright Year	2015
Abstract	Anterior segment optical coherent tomography (AS-OCT, Visante; Zeiss) is used to examine meridional variation in anterior scleral thickness (AST) and its association with refractive error, ethnicity and gender. Scleral cross-sections of 74 individuals (28 males; 46 females; aged between 18-40 years (27.7±5.3)) were sampled twice in random order in 8 meridians: [superior (S), inferior (I), nasal (N), temporal (T), superior-temporal (ST), superior-nasal (SN), inferior-temporal (IT) and inferior-nasal (IN)]. AST was measured in 1mm anterior-to-posterior increments (designated the A-P distance) from the scleral spur (SS) over a 6mm distance. Axial length and refractive error were measured with a Zeiss IOLMaster biometer and an open-view binocular Shin-Nippon autorefractor. Intra- and inter-observer variability of AST was assessed for each of the 8 meridians. Mixed repeated measures ANOVAs tested meridional and A-P distance differences in AST with refractive error, gender and ethnicity. Only right eye data were analysed. AST (mean±SD) across all meridians and A-P distances was 725±46μm. Meridian SN was the thinnest (662±57μm) and I the thickest (806±60μm). Significant differences were found between all meridians (p<0.001), except S:ST, IT:IN, IT:N and IN:N. Significant differences between A-P distances were found except between SS and 6 mm and between 2 and 4 mm. AST measurements at 1mm (682±48 μm) were the thinnest and at 6mm (818±49 μm) the thickest (p<0.001); a significant interaction occurred between meridians and A-P distances (p<0.001). AST was significantly greater (p<0.001) in male subjects but no significant differences were found between refractive error or ethnicity. Significant variations in AST occur with regard to meridian and distance from the SS and may have utility in selecting optimum sites for pharmaceutical or surgical intervention.
Related Links	http://dx.doi.org/10.1371/journal.pone.0132902
Starting Page	132902
File Format	PDF
ISSN	19326203
e-ISSN	19326203
Journal	PLoS ONE
Issue Number	7
Volume Number	10
Language	English
Publisher	Public Library of Science
Publisher Date	2015-07-28
Access Restriction	Open
Rights Holder	Public Library of Science
Subject Keyword	Research in Higher Education
Content Type	Text
Resource Type	Article
Subject	Multidisciplinary

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Assessment of anterior scleral thickness in Turkish open angle glaucoma patients: an anterior segment optical coherence tomography study

Reproducibility of Scleral Spur Identification and Angle Measurements Using Fourier Domain Anterior Segment Optical Coherence Tomography

EVALUATION OF THE EFFECT OF INTRAVITREAL BEVACIZUMAB INJECTION ON SCLERAL THICKNESS WITH ANTERIOR SEGMENT OPTICAL COHERENCE TOMOGRAPHY

EVALUATION OF THE EFFECT OF INTRAVITREAL BEVACIZUMAB INJECTION ON SCLERAL THICKNESS WITH ANTERIOR SEGMENT OPTICAL COHERENCE TOMOGRAPHY

In Vivo Intraocular Lens Thickness Measurement and Power Estimation Using Optical Coherence Tomography

Measurement of corneal and limbal epithelial thickness by anterior segment optical coherence tomography and in vivo confocal microscopy

Comparison of Central Corneal Thickness using Anterior Segment Optical Coherence Tomography versus Ultrasound Pachymetry

Reproducibility of Scleral Spur Identification and Angle Measurements Using Fourier Domain Anterior Segment Optical Coherence Tomography

Assessment of corneal thickness measurement using swept-source Fourier-domain anterior segment optical coherence tomography and Scheimpflug camera.

Measurement of Scleral Thickness in Humans Using Anterior Segment Optical Coherent Tomography

Similar Documents

Assessment of anterior scleral thickness in Turkish open angle glaucoma patients: an anterior segment optical coherence tomography study

Reproducibility of Scleral Spur Identification and Angle Measurements Using Fourier Domain Anterior Segment Optical Coherence Tomography

EVALUATION OF THE EFFECT OF INTRAVITREAL BEVACIZUMAB INJECTION ON SCLERAL THICKNESS WITH ANTERIOR SEGMENT OPTICAL COHERENCE TOMOGRAPHY

EVALUATION OF THE EFFECT OF INTRAVITREAL BEVACIZUMAB INJECTION ON SCLERAL THICKNESS WITH ANTERIOR SEGMENT OPTICAL COHERENCE TOMOGRAPHY

In Vivo Intraocular Lens Thickness Measurement and Power Estimation Using Optical Coherence Tomography

Measurement of corneal and limbal epithelial thickness by anterior segment optical coherence tomography and in vivo confocal microscopy

Comparison of Central Corneal Thickness using Anterior Segment Optical Coherence Tomography versus Ultrasound Pachymetry

Reproducibility of Scleral Spur Identification and Angle Measurements Using Fourier Domain Anterior Segment Optical Coherence Tomography

Assessment of corneal thickness measurement using swept-source Fourier-domain anterior segment optical coherence tomography and Scheimpflug camera.

Measurement of Scleral Thickness in Humans Using Anterior Segment Optical Coherent Tomography