NDLI: Electrical conductivity measurement in Thiel-embalmed tissue model: relevance to radiofrequency ablation

Content Provider	IET Digital Library
Author	Wang, Zhigang Luo, Hongyan Nick, M. Gueorguieva, M. Andre, P. Baker, R. T. Lean, D. Mc Brown, S. Cuschieri, A.
Abstract	Thiel-embalmed human cadaveric specimens are used widely for biomedical scientific investigation. This Letter reports electrical impedance measurements of Thiel-embalming solutions from 1 Hz to 32 MHz. Compared with other solutions studied, Thiel solution has the lowest impedance throughout the test spectrum. The electrical conductivity of a Thiel-embalmed liver sample exhibited a relatively flat frequency response from 100 to 500 kHz, which is the frequency range used for electro-surgery and radiofrequency tumour ablation (RFA). It measured 5 Sm−1 compared with 0.22 Sm−1 obtained from ex-vivo fresh pig liver. Using finite element modelling and experimental evaluation, the ablation zone obtained from the Thiel-embalmed liver sample was extremely small due to its much higher conductivity. Hence, it is concluded that Thiel-embalmed tissue cannot be used as a reliable model for RFA evaluation.
Starting Page	1125
Ending Page	1127
Page Count	3
ISSN	00135194
Volume Number	50
e-ISSN	1350911X
Issue Number	Issue 16, Jul (2014)
Alternate Webpage(s)	https://digital-library.theiet.org/content/journals/el/50/16
Alternate Webpage(s)	https://digital-library.theiet.org/content/journals/10.1049/el.2014.1934
Journal	Electronics Letters
Publisher Date	2014-07-22
Access Restriction	Open
Rights Holder	© The Institution of Engineering and Technology
Subject Keyword	Bioelectric Phenomena Bioelectric Signal Bioelectricity Biological Tissues Biomedical Measurement Biomedical Scientific Investigation Electric Impedance Measurement Electrical Activity in Neurophysiological Processes Electrical Conductivity Electrical Conductivity Measurement Electrical Impedance Measurement Electro surgery Ex-vivo Fresh Pig Liver Finite Element Analysis Finite Element Modelling Frequency 1 Hz to 32 MHz Frequency 100 KHz to 500 KHz Impedance And Admittance Measurement Liver Numerical Approximation And Analysis Patient Care And Treatment Physiological Model Radiofrequency Ablation Radiofrequency Tumour Ablation Reliable Model RFA Evaluation Surfactant Thiel-embalmed Human Cadaveric Specimens Thiel-embalmed Liver Sample Thiel-embalmed Tissue Model Thiel-embalming Solution Tumours
Content Type	Text
Resource Type	Article
Subject	Electrical and Electronic Engineering

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