NDLI: Electrical conductivity measurement in thiel-embalmed tissue model: relevance to radiofrequency ablation

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Electrical conductivity measurement in thiel-embalmed tissue model: relevance to radiofrequency ablation

Content Provider	Semantic Scholar
Author	Wang, Zhigang Luo, Hongyan Nick, Morteza Gueorguieva, Mariana André, Pascal Baker, Richard Thomas McLean, Donald Brown, Stuart I. Cuschieri, Alfred
Copyright Year	2014
Abstract	Thiel-embalmed human cadaveric specimens are used widely for biomedical scientific investigation. This Letter reports electrical impedance measurements of Thiel-embalming solutions from 1 Hz to 32 MHz. Compared with other solutions studied, Thiel solution has the lowest impedance throughout the test spectrum. The electrical conductivity of a Thiel-embalmed liver sample exhibited a relatively flat frequency response from 100 to 500 kHz, which is the frequency range used for electro-surgery and radiofrequency tumour ablation (RFA). It measured 5 Sm−1 compared with 0.22 Sm−1 obtained from ex-vivo fresh pig liver. Using finite element modelling and experimental evaluation, the ablation zone obtained from the Thiel-embalmed liver sample was extremely small due to its much higher conductivity. Hence, it is concluded that Thiel-embalmed tissue cannot be used as a reliable model for RFA evaluation.
Starting Page	1125
Ending Page	1127
Page Count	3
File Format	PDF HTM / HTML
DOI	10.1049/el.2014.1934
Volume Number	50
Alternate Webpage(s)	https://research-repository.st-andrews.ac.uk/bitstream/handle/10023/6141/baker2014electroniclett1125.pdf;sequence=1
Alternate Webpage(s)	https://doi.org/10.1049/el.2014.1934
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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