NDLI: Recording properties of an electrode implanted in the peripheral nervous system: A human computational model

Content Provider	IEEE Xplore Digital Library
Author	Jehenne, B. Raspopovic, S. Capogrosso, M. Arleo, A. Micera, S.
Copyright Year	2015
Description	Author affiliation: Inst. de la Vision, Paris, France (Arleo, A.) \|\| Ecole Polytech. Fed. de Lausanne (EPFL), Lausanne, Switzerland (Jehenne, B.; Raspopovic, S.; Capogrosso, M.; Micera, S.)
Abstract	Chronically implanted neural interfaces are aiming to create an intimate and long-term contact with neural cells. This would potentially allow the development of neurocontrolled artificial devices. However the precise nature of the compound signal recorded and the interaction between the neural population and the electrode are still poorly understood. Consequently there is limited knowledge available on the optimal strategy for the design of peripheral electrodes in order to achieve high information harvest while insuring long-term reliability of the device. In this paper, we introduce a novel integrated hybrid Finite Elements/Biophysical model for recording, based on anatomical data of the human median nerve. Using this model, we simulated the signal recorded intrafascicularly with implanted Transversal Intraneural Multichannel Electrode (TIME). The preliminary results help in understanding the properties of recorded signals and suggest that a substantial portion of the spikes detected with electrodes implanted in the peripheral nervous system might actually be multi-unit events formed by the superposition of several fibers activity.
Starting Page	482
Ending Page	485
File Size	1456182
Page Count	4
File Format	PDF
ISBN	9781467363891
DOI	10.1109/NER.2015.7146664
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2015-04-22
Publisher Place	France
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Electrodes Shape Computational modeling Biological system modeling Sociology Finite element analysis Statistics
Content Type	Text
Resource Type	Article

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4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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