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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Rui Cao Lu Bai Na Ji Yinghao Gao Yuanmou Chen Erbing Hua |
| Copyright Year | 2011 |
| Description | Author affiliation: Tianjin Key Laboratory of Industry Microbiology, College of Biotechnology, China (Lu Bai) || Tianjin University of Science & Technology, China (Erbing Hua) || Key Laboratory of Industrial Microbiology, Ministry of Education, College of Biotechnology, China (Rui Cao) || Tianjin, 300457, China (Na Ji; Yinghao Gao; Yuanmou Chen) |
| Abstract | Resveratrol (3,5,4′-trihydroxy-trans-stilbene) is a stilbenoid, a type of natural phenol, and a phytoalexin produced naturally by several kinds of plants when under attack by pathogens such as bacteria or fungi which exerts a variety of biological activities. In this work, several resveratrol derivatives were designed and synthesized through a four-step convenient synthetic procedure. Six newly synthesized compounds were characterized on the basis of $^{1}H$ NMR and mass spectra. Also, these compounds were tested for their biological activities against $Gram^{+}$ and $Gram^{−}$ bacteria. Through the analysis on the results of the anti-bacterial activity test, a preliminary structure-activity relationship was obtained which indicated that the trans-stilbene structure and the phenolic hydroxyl group (also the acetoxyl group), especially the para-phenolic hydroxyl group are the two key structures for their anti-bacterial activities in this type of molecules. |
| Starting Page | 449 |
| Ending Page | 452 |
| File Size | 104690 |
| Page Count | 4 |
| File Format | |
| ISBN | 9781612847016 |
| e-ISBN | 9781612847047 |
| DOI | 10.1109/ITiME.2011.6130873 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2011-12-09 |
| Publisher Place | China |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | resveratrol derivatives Microwave integrated circuits anti-bacterial activity Microorganisms Heck reaction Solids Anti-bacterial Nuclear magnetic resonance Compounds |
| Content Type | Text |
| Resource Type | Article |
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