NDLI: A CMOS pancreatic islet of Langerhans for automatic glycemic regulation

Content Provider	IEEE Xplore Digital Library
Author	Banks, D. Morris, C. Omeru, J. Wang Wei Georgiou, P. Toumazou, C.
Copyright Year	2011
Description	Author affiliation: Centre for Bio-Inspired Technology, Imperial College London, UK (Banks, D.; Morris, C.; Omeru, J.; Wang Wei; Georgiou, P.; Toumazou, C.)
Abstract	We present here a CMOS islet of Langerhans. This circuit mimics the cellular dynamics of the pancreatic alpha and beta cells that control blood glucose levels, through the release of the hormones glucagon and insulin. This system has been designed using human glycemic in vivo blood measurements and mammalian in vitro cell data. This integrated silicon pancreatic islet can form the control algorithm of an artificial pancreas for patients with type 1 diabetes mellitus. The circuit is designed in a 0.35 µm standard CMOS process; is low-power, dissipating 78 µW, can interface directly with the current output from a glucose sensor and outputs dual pump control signals for the release of the glycemic regulatory hormones.
Starting Page	261
Ending Page	264
File Size	528764
Page Count	4
File Format	PDF
ISBN	9781457714696
e-ISBN	9781457714702
DOI	10.1109/BioCAS.2011.6107777
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2011-11-10
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Data models Biochemistry Silicon Diabetes Mathematical model Insulin Sugar
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
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