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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Lu Zhang Xin Zhao Xingyu Chen Kaixing Li Yunfei Xing Wei Chen Hong Zhao Zhuangde Jiang Li Yuan Nianling Yao |
| Copyright Year | 2015 |
| Description | Author affiliation: Dept. of Lab. Med., Xi'an Jiaotong Univ., Xi'an, China (Wei Chen; Li Yuan) || Xijing Hosp., Fourth Mil. Med. Univ., Xi'an, China (Nianling Yao) || State Key Lab. for Manuf. Syst. Eng., Xi'an Jiaotong Univ., Xi'an, China (Lu Zhang; Xin Zhao; Xingyu Chen; Kaixing Li; Yunfei Xing; Hong Zhao; Zhuangde Jiang) |
| Abstract | The 2D and 3D scattering intensity spectra of label free clinical lymphocyte cells which are in both normal growing state and abnormal pathological states are studied according to three dimensional finite-difference time-domain (FDTD) simulation results. The correlation of intensity spectra and scattering images in different spatial regions are discussed for different cells' structural differences during their pathological changing processes. Some important ground truths which can be effectively adopted for distinguish lymphocyte cells from healthy ones in human peripheral blood without any dying or label techniques are put forward. The research results would be very important to fully discover cells spatial scattering features and provide more reliable sorting criterions for label free cells detection technologies. |
| Starting Page | 1712 |
| Ending Page | 1717 |
| File Size | 905612 |
| Page Count | 6 |
| File Format | |
| e-ISBN | 9781479983896 |
| DOI | 10.1109/ICIEA.2015.7334387 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2015-06-15 |
| Publisher Place | New Zealand |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Scattering Finite difference methods Cells (biology) Time-domain analysis Biomembranes Three-dimensional displays Blood spectrum label free lymphocyte scattering |
| Content Type | Text |
| Resource Type | Article |
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