NDLI: Joining microelectronics and microionics: Nerve cells and brain tissue on semiconductor chips

Content Provider	IEEE Xplore Digital Library
Author	Fromherz, P.
Copyright Year	2007
Description	Author affiliation: Max Planck Inst. for Biochem., Munich (Fromherz, P.) The direct electrical interfacing of semiconductor chips with individual nerve cells and with brain tissue is considered. At first, the structure of the cell-chip contact is described and then the electrical coupling is characterized between ion channels, the electrical elements of nerve cells, and transistors and capacitors of silicon chips. On that basis the signal transmission between microelectronics and microionics is implemented in both directions. Simple hybrid neuroelectronic systems are assembled with neuron pairs and with small neuronal networks. Finally, the interfacing with capacitors and transistors is extended to brain tissue on silicon. The application of CMOS chips with capacitively coupled recording and stimulation sites allows an imaging of neuronal activity with high spatiotemporal resolution. Goal of the work in an integration of neuronal network dynamics and digital electronics on a microscopic level for applications in brain research, medical prosthetics and information technology.
Starting Page	36
Ending Page	45
File Size	740387
Page Count	10
File Format	PDF
ISBN	9781424411238
ISSN	19308876
e-ISBN	9781424411245
DOI	10.1109/ESSDERC.2007.4430878
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2007-09-11
Publisher Place	Germany
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Microelectronics Brain Couplings Capacitors Silicon Biological neural networks Contacts Assembly systems Neurons High-resolution imaging
Content Type	Text
Resource Type	Article

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