NDLI: Localized nucleic acid delivery to living cells using nanobiotechnology approaches

Content Provider	IEEE Xplore Digital Library
Author	Plank, C. Schillinger, U. Hacker, C. Brill, T. Rudolph, C. Krotz, F. Hirschberger, J. Stemberger, A. Gansbacher, B.
Copyright Year	2004
Description	Author affiliation: Inst. of Exp. Oncology, Tech. Univ., Munich, Germany (Plank, C.; Schillinger, U.; Hacker, C.; Brill, T.)
Abstract	Nucleic acids delivered to cells are powerful research tools and promising therapeutics. Spatial and temporal control of delivery is essential for the efficacy, safety and specificity of the application. The shuttles for nucleic acid delivery, so-called vectors, are nanometric biological or synthetic entities comprising complex biological functionalities. We localize nucleic acid delivery exploiting carrier materials. These are on the one hand implantable biomaterials doted with vectors for tissue engineering purposes, on the other hand magnetic nanoparticles associated with vectors which can be magnetically directed to a target site. We pursue these approaches to provide novel tools for research and therapy.
Starting Page	242
Ending Page	244
File Size	246210
Page Count	3
File Format	PDF
ISBN	0780385365
DOI	10.1109/NANO.2004.1392311
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2004-08-16
Publisher Place	Germany
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Nanobiotechnology Safety Magnetic confinement DNA Nanobioscience Biological information theory Tissue engineering Medical treatment Drug delivery RNA
Content Type	Text
Resource Type	Article

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4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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