NDLI: Study of the capabilities of the Timepix detector for Ion Beam radiotherapy applications

Content Provider	IEEE Xplore Digital Library
Author	Martisikova, M. Hartmann, B. Gwosch, K. Jakubek, J. Granja, C. Jakel, O.
Copyright Year	2012
Description	Author affiliation: Heidelberg Univ. Hosp., Heidelberg, Germany (Martisikova, M.; Hartmann, B.; Jakel, O.) \|\| Inst. of Exp. & Appl. Phys., Czech Tech. Univ. in Prague, Prague, Czech Republic (Jakubek, J.; Granja, C.) \|\| German Cancer Res. Center - DKFZ, Heidelberg, Germany (Gwosch, K.)
Abstract	The finite range of ion beams in matter and the presence of the Bragg-peak at the end of their range enable to create highly localized dose distributions. This advantage represents at the same time a challenge - namely to control all factors influencing the dose distribution with high precision. To ensure the required quality of the dose distribution applied to the patient, a number of measurement procedures is conducted. Many of these techniques were adopted from photon beam radiotherapy. Improvements in terms of the information amount gained are expected from new generations of dedicated ion detection techniques. One of the possible research directions is given by semiconductor-based detectors, which are at present rarely used in ion beam radiotherapy. In this contribution we report on the studies of the capabilities of the Timepix detector. This hybrid semiconductor pixelated detector was developed by the Medipix Collaboration at CERN. Its high spatial resolution allows an online registration of single ions. Experiments were performed at the Heidelberg Ion Beam Therapy Center in Germany using carbon ion beams. The signal pattern of single ions in the detector signal was shown to provide separation of the primary and different types of secondary ions. The direction of the secondary ions emerging from different irradiated phantoms were measured using 3D voxel detector containing several Timepix layers. The analysis of the recorded ion tracks shows a correlation with the beam range, position and width, which are all of high interest for monitoring of the beam within the patient during the therapy delivery. The results of the discussed studies show that the Timepix detector offers attractive capabilities for the needs of carbon ion beam therapy.
Sponsorship	IEEE Nucl. Plasma Sci. Soc
Starting Page	4324
Ending Page	4328
File Size	1021718
Page Count	5
File Format	PDF
ISBN	9781467320283
ISSN	10823654
e-ISBN	9781467320306
DOI	10.1109/NSSMIC.2012.6551985
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2012-10-27
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	therapy delivery monitoring carbon ion beam fragmentation secondary ions ion distinction 3D silicon tracking detector
Content Type	Text
Resource Type	Article

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