NDLI: Evaluation of different random estimation methods for the MADPET-II small animal PET scanner using GATE

Content Provider	IEEE Xplore Digital Library
Author	Torres-Espallardo, I. Rafecas, M. Spanoudaki, V.Ch. McElroy, D.P. Ziegler, S.I.
Copyright Year	2006
Description	Author affiliation: Nuklearmedizinische Klinik, Technische Univ. Muenchen (Torres-Espallardo, I.)
Abstract	The validity of random estimation techniques has been studied for various low energy thresholds (LETs) for singles list-mode simulated data sets of the MADPET-II small animal PET scanner. MADPET-II is a dual layer PET scanner prototype consisting of LSO crystals read individually from avalanche photodiodes (APDs). The simulations have been performed using GATE simulation toolkit. Several sources have been simulated, such as point, planar, cylindrical and Derenzo. We have evaluated the randoms using three standard methods, the delayed window (DW), singles rate (SR) and time histogram fitting (THF). In addition, we know from simulations how to discriminate between random and true coincidences. Therefore, we compare the randoms estimated with the above methods with the number of randoms obtained using GATE information. An overestimation in the number of randoms has been observed for DW and SR methods. We pointed out that this mismatch is due to the inter-crystal scatter (events that take place between the crystals) since is reduced for LETs higher than 255 keV. Nevertheless, this discrepancy does not have a significant effect to the quality of the reconstructed images.
Starting Page	3148
Ending Page	3150
File Size	862049
Page Count	3
File Format	PDF
ISBN	1424405602
ISSN	10957863
DOI	10.1109/NSSMIC.2006.356542
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2006-10-29
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Animals Positron emission tomography Crystals Strontium Prototypes Avalanche photodiodes Delay effects Histograms Scattering Image reconstruction inter-crystal scatter PET small animal GATE random estimation individual read-out
Content Type	Text
Resource Type	Article

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
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4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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