NDLI: Performance Evaluation of a Prototype Micro-CT System

Content Provider	IEEE Xplore Digital Library
Author	Seungryong Cho Junguo Bian Pelizzari, C.A. Souris, J.S. Chin-Tu Chen Xiaochuan Pan
Copyright Year	2006
Description	Author affiliation: Comm. on Med. Phys., Chicago Univ., IL (Seungryong Cho; Junguo Bian; Pelizzari, C.A.; Souris, J.S.; Chin-Tu Chen; Xiaochuan Pan)
Abstract	Small animal imaging is becoming an important screening tool for laboratory animals with transplanted diseases. Micro-computed tomography (micro-CT) is one of the most popular choices for small animal imaging because of its high spatial resolution and high signal-to-noise ratio. Recently, we have built a cone-beam micro-CT system based on a Faxitron micro-specimen radiographic system. The system consists of a microfocal X-ray source, a rotary stage with object holder, and a CsI-coupled CMOS detector. The presampling modulation transfer function (MTF) was measured and a geometric calibration procedure for this prototype system was performed. The projection data of mice were obtained and corrected based on the parameters obtained by geometric calibration procedure. Results of the studies show promising applicability to small animal imaging and also to investigating new image reconstruction algorithms.
Starting Page	3127
Ending Page	3129
File Size	230463
Page Count	3
File Format	PDF
ISBN	1424405602
ISSN	10957863
DOI	10.1109/NSSMIC.2006.356537
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2006-10-29
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Prototypes Animals High-resolution imaging Calibration Laboratories Diseases Tomography Optical imaging Spatial resolution Signal to noise ratio Geometric Calibration micro-CT MTF
Content Type	Text
Resource Type	Article

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