NDLI: Clinical comparison of HiRez versus non-HiRez LSO crystal sampling for lesion detection and SUV quantification

Content Provider	IEEE Xplore Digital Library
Author	Hapdey, S. Vauclin, S. Manrique, A. Buvat, I. Fourcade, M. de Dreuille, O. Gardin, I. Vera, P.
Copyright Year	2006
Description	Author affiliation: Dept. of Nucl. Medicine, Rouen Univ. Hosp. (Hapdey, S.)
Abstract	The aim of this work was to evaluate the clinical impact the new HiRez crystal arrangement (Biograph PET scanner) on lesions detection and quantification. Twelve non-HiRez patient sinograms were generated from the original HiRez sinograms. Data conversion (smoothing) from HiRez to non-HiRez geometry was based on real acquisitions and Monte-Carlo simulations of point sources in air for the HiRez and non-HiRez models. The averaged tumor volume reduction on the HiRez images compared to the non-HiRez images for the 41 lesions considered was -13.9 plusmn 19.4% (p < 0.01, paired t-test). Although significant SUVs modifications were found (Max SUVs were statistically higher in HiRez images than in non-HiRez images: 4.2 plusmn 3.1 vs 4.0 plusmn 2.9 respectively; p < 0.001), no difference was observed in terms of lesion detection in our small series, possibly due to lesion characteristics (isolated lesions, high tissue-to-background ratio).
Starting Page	3094
Ending Page	3096
File Size	2772356
Page Count	3
File Format	PDF
ISBN	1424405602
ISSN	10957863
DOI	10.1109/NSSMIC.2006.356528
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2006-10-29
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Sampling methods Lesions Crystals Biomedical imaging Nuclear medicine Positron emission tomography Neoplasms Hospitals Nuclear and plasma sciences Data conversion
Content Type	Text
Resource Type	Article

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