NDLI: Development of micro particles separation device with piezo-ceramic vibrator

Content Provider	IEEE Xplore Digital Library
Author	Ooe, K. Fukuda, T.
Copyright Year	2009
Description	Author affiliation: Dept. of Micro-System Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan (Fukuda, T.) \|\| Graduate School of Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan (Ooe, K.)
Abstract	During hemanalysis, it is necessary to separate blood cells from whole blood. Many blood separation methods, for example, centrifugation and filtering, are in practical use. However, the use of these methods involves problems from the perspectives of processing speed and processing volume. We develop new types of blood separation devices that use piezo-ceramic vibrators. The first device uses a capillary. One end of the capillary is fixed to the device frame, and the other is fixed to a piezo-ceramic vibrator. The vibrator transmits bending waves to the capillary. This device can process only a small amount of solution; therefore, it is not suitable for hemanalysis. In order to solve this problem, we developed a second device; this device has a pair of thin glass plates with a small gap as a substitute for the capillary used in the first device. These devices are based on the fact that particles heavier than water move toward transverse velocity antinodes while those lighter than water move toward velocity nodes. In this report, we demonstrate the high-speed separation of silica microbeads and 50-vol% glycerol water by using these devices. The first device can separate the abovementioned solution within 3 min while the second can separate it within 1 min. Both devices are driven by a rectangular wave of 15 to 20 Vpp. Furthermore, it has been confirmed that red blood cells are separated from diluted whole blood using the first device within approximately 1 min. These devices have transparency, so they can compose as the analysis system with the chemical analyzer easily.
Starting Page	56
Ending Page	61
File Size	1515463
Page Count	6
File Format	PDF
ISBN	9781424450947
DOI	10.1109/MHS.2009.5352095
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2009-11-09
Publisher Place	Japan
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Cells (biology) Testing Red blood cells Plasma applications Plasma devices Chemical analysis Filtration Prototypes Filtering Diseases
Content Type	Text
Resource Type	Article

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