NDLI: An investigation into sub-optimal control on the downstream processing of a large scale industrial process

Content Provider	IEEE Xplore Digital Library
Author	Goldrick, S. Lennox, B. Smith, K. Lovett, D. Montague, G.
Copyright Year	2012
Description	Author affiliation: Perceptive Engineering Limited, Daresbury Innovation Centre, Keckwick Lane, Daresbury, Cheshire, UK (Smith, K.; Lovett, D.) \|\| Biopharmaceutical Bioprocess Technology Centre, Merz Court, Newcastle University, Newcastle-upon-Tyne, UK (Goldrick, S.; Montague, G.) \|\| Control Systems Group, School of Electrical and Electronic Engineering, University of Manchester, UK (Lennox, B.)
Abstract	Industrial processes can be divided into two main areas: upstream processing; involving the manufacture of product and downstream processing; product separation and purification. Although both of these operations are necessary to obtain the final product; optimisation and improvement efforts are generally biased towards upstream processing. The importance of downstream processing can often be neglected to concentrate on the “more important” aspect of upstream processing. However, if the purification and separation steps aren't controlled effectively it can result in a significant reduction in the overall process yield. This investigation focuses on the control of a two stage counter current liquid-liquid extraction unit downstream of a batch process. A reduced separation capacity of this process is observed due to a flow oscillation in the solvent stream. The cause of this oscillation is investigated by analysing process variable behaviour, paying particular attention to the interplay between the control strategy and disturbances of the process. The effect on separation efficiency is shown through high frequency analysis of product concentrate in the output stream. The aim of this work is to highlight the importance of the process control strategy. Reviewing the linkages between the process controls, product yield and quality are essential as part of a continuous improvement strategy. Such reviews can highlight opportunities for significant increases in yield that are often masked out through infrequent sampling procedures.
Starting Page	277
Ending Page	280
File Size	2049856
Page Count	4
File Format	PDF
ISBN	9781467315593
e-ISBN	9781467315609
e-ISBN	9781467315586
DOI	10.1109/CONTROL.2012.6334642
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2012-09-03
Publisher Place	United Kingdom
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Shafts Solvents Liquids Process control Valves Market research Oscillators
Content Type	Text
Resource Type	Article

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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