NDLI: Trajectory tracking of batch product quality using intermittent measurements and moving window estimation

Content Provider	IEEE Xplore Digital Library
Author	Jian Wan Marjanovic, O. Lennox, B.
Copyright Year	2012
Description	Author affiliation: Control Systems Center, School of Electrical and Electronic Engineering, The University of Manchester, M13 9PL, UK (Jian Wan; Marjanovic, O.; Lennox, B.)
Abstract	In order to meet tight product quality specifications for batch/fed-batch processes, it is vital to monitor and control batch product quality throughout the batch duration. The ideal strategy is to control batch product quality through trajectory tracking of a desirable batch product quality evolution during the batch run. However, due to the lack of in-situ sensors for continuous measurements of batch product quality, the measurement of batch product quality is usually implemented by laboratory assay of samples and thus these measurements are generally intermittent. Therefore direct trajectory tracking of batch product quality is not feasible for such scenarios with intermittent measurements. This paper proposes an approach to use intermittent measurements to realize trajectory tracking control of batch product quality through moving window estimation. The first step of the approach is to identify a partial least squares (PLS) model using intermittent measurements to relate process variable trajectories and batch product quality. Then the identified PLS model is further applied to predict product quality trajectory during the batch run so as to realize trajectory tracking of a desirable product quality evolution. An example from fed-batch fermentation for penicillin production is used to illustrate the principle and the effectiveness of the proposed approach.
Starting Page	265
Ending Page	270
File Size	835063
Page Count	6
File Format	PDF
ISBN	9781467315593
e-ISBN	9781467315609
e-ISBN	9781467315586
DOI	10.1109/CONTROL.2012.6334640
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2012-09-03
Publisher Place	United Kingdom
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Estimation Predictive models Product design Data models Trajectory Quality assessment Principal component analysis
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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