NDLI: Graphitic Materials for RF Thermal Ablation of Tumors

Content Provider	IEEE Xplore Digital Library
Author	Mahmood, M. Yang Xu Zhongrui Li Dervishi, E. Ali, N. Saini, V. Biris, A.S. Trigwell, S. Zharov, V.P. Biris, A.R. Lupu, D.
Copyright Year	2008
Description	Author affiliation: Appl. Sci. Dept., Univ. of Arkansas at Little Rock, Little Rock, AR (Mahmood, M.; Yang Xu; Zhongrui Li; Dervishi, E.; Ali, N.; Saini, V.; Biris, A.S.)
Abstract	Graphitic nanomaterials have been synthesized by chemical vapor deposition in different morphologies, sizes and shapes. After being administered to cancerous HeLa cells cultures for 24 hours, it was found that they were uptaken inside various subcompartments of the cells. The surface charge was observed to play a major role if the cells were absorbed with predilection inside the cytoplasm or the nucleus. Radio-Frequency electromagnetic radiation of 350 KHz was applied to the cell cultures and it was found that the graphitic materials are strong absorbers of such radiation, fact which was reflected into a higher localized heating inside the cells. The nanoparticles were found to create localized damage at the level of DNA and various membranes, which was reflected in the inducement of apoptosis of the cells. Various experimental conditions and how they correspond to the cell death observations are presented as well.
Starting Page	1
Ending Page	6
File Size	743312
Page Count	6
File Format	PDF
ISBN	9781424422784
ISSN	01972618
DOI	10.1109/08IAS.2008.86
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2008-10-05
Publisher Place	Canada
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Radio frequency Nanoparticles Electromagnetic heating Shape Surface morphology DNA Electromagnetic radiation Nanomaterials Chemical vapor deposition Neoplasms
Content Type	Text
Resource Type	Article
Subject	Industrial and Manufacturing Engineering Control and Systems Engineering Electrical and Electronic Engineering

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