NDLI: Stochastic Modeling and Analysis of Genetic Networks

Content Provider	IEEE Xplore Digital Library
Author	Khammash, M. Samad, H.E.
Copyright Year	2005
Description	Author affiliation: Department of Mechanical Engineering, University of California at Santa Barbara, Santa Barbara, CA 93106, USA khammash@engr.ucsb.eduand (Khammash, M.)
Abstract	Much of the mathematical modeling of genetic networks represents gene expression and regulation as deterministic processes. There is now, however, considerable experimental evidence indicating that significant stochastic fluctuations are present in these processes. Stochasticity is an inherent feature of biological dynamics, and as such, should be the subject of in-depth analysis. The investigation of stochastic properties in genetic systems involves the formulation of a correct representation of molecular noise, followed by the formulation of mathematically sound approximations for these representations. It also involves devising efficient computational algorithms capable of tackling the complexity of the dynamics involved. In this paper we review a number of these techniques and provide compelling examples that illustrate the richness of phenomena that can result from the interaction of dynamics and noise in genetic networks.
Starting Page	2320
Ending Page	2325
File Size	1717849
Page Count	6
File Format	PDF
ISBN	0780395670
DOI	10.1109/CDC.2005.1582508
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2005-12-15
Publisher Place	Spain
Access Restriction	Subscribed
Rights Holder	IEEE/EUCA
Subject Keyword	Stochastic processes Genetics Stochastic resonance Acoustic noise Biological system modeling Mathematical model Gene expression Fluctuations Stochastic systems Biology computing
Content Type	Text
Resource Type	Article

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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