NDLI: Influence of left atrial geometry on rotor core trajectories in a model of atrial fibrillation

Content Provider	IEEE Xplore Digital Library
Author	Tzortzis, Konstantinos N. Roney, Caroline H. Qureshi, Norman A. Ng, Fu Siong Lim, Phang Boon Sherwin, Spencer J. Peters, Nicholas S. Cantwell, Chris D.
Copyright Year	2015
Description	Author affiliation: Imperial College London, United Kingdom (Tzortzis, Konstantinos N; Roney, Caroline H; Qureshi, Norman A; Ng, Fu Siong; Lim, Phang Boon; Sherwin, Spencer J; Peters, Nicholas S; Cantwell, Chris D)
Abstract	Left atrial anatomy and myocardial architecture are known to influence rotor initiation and maintenance. However, identifying their relative contribution clinically is challenging. The present study aims to investigate in silico the effect of left atrial geometry in isolation on rotor generation and evolution through the spatiotemporal tracking of phase singularities. After meandering for a short period of time, rotors are attracted to specific areas of the chamber where there is high curvature, primarily near the base of the left atrial appendage and the junctions of the pulmonary veins. This suggests that the left atrial anatomy could play a key role in the perpetuation of fibrillatory activity.
Starting Page	481
Ending Page	484
File Size	1066740
Page Count	4
File Format	PDF
ISBN	9781509006854
ISSN	2325887X
e-ISBN	9781509006847
DOI	10.1109/CIC.2015.7408691
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2015-09-06
Publisher Place	France
Access Restriction	Subscribed
Rights Holder	Creative Commons Attribution License 2.5 (CCAL)
Subject Keyword	Rotors Trajectory Computational modeling Numerical models Catheters Spatiotemporal phenomena Biological system modeling
Content Type	Text
Resource Type	Article
Subject	Computer Science Cardiology and Cardiovascular Medicine

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4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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