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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Tai Cheng-Jeng Wang Wei-Hsu Chen Po-Min Hsieh Jui-Chien |
| Copyright Year | 1999 |
| Description | Author affiliation: Sect. of Med. Oncology, Nat. Yang-Ming Univ., Taipei, Taiwan (Tai Cheng-Jeng) |
| Abstract | The blood perfusion of some tumors is relatively low and poorly responsive to hyperthermia therapy. As a result, the blood now provides relatively little heat sinking for tumors We hypothesized that the the final gradient between tumors and normal tissues could be increased by applying energy only during the pulsation of arteries. Tests of the hypothesis were done by using a finite element model, which simulated a tumor surrounded by normal tissues and this tumor received either continuous or pulsatile heat, together with the pulsatile blood flow. Our results indicated there was a thermal gradient of 8/spl deg/C between pulsatile and continuous powers on heat delivery. Established values for tissues and tumors were incorporated into this model and it facilitated prediction of the possible results of hyperthermia therapy. |
| File Size | 96655 |
| File Format | |
| ISBN | 0780356748 |
| ISSN | 1094687X |
| DOI | 10.1109/IEMBS.1999.804440 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 1999-10-13 |
| Publisher Place | USA |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Hyperthermia Medical treatment Neoplasms Computer simulation Heat transfer Blood flow Finite element methods Predictive models Computational modeling Medical simulation |
| Content Type | Text |
| Resource Type | Article |
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