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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Sarraf, S. Marzbanrad, E. Mobedi, H. |
| Copyright Year | 2014 |
| Description | Author affiliation: Rotman Res. Inst. at Baycrest, Toronto, ON, Canada (Sarraf, S.) || Iran Polymer & Petrochem. Inst., Tehran, Iran (Mobedi, H.) || Dept. of Mech. & Mechatron. Eng., Univ. of Waterloo, Waterloo, ON, Canada (Marzbanrad, E.) |
| Abstract | This paper examines the application of mathematical modeling to a novel drug delivery system using artificial neural networks. For this purpose, a Feed-Forward back propagation network was trained by two different concepts and the behavior of this drug delivery system was analyzed based on the simulated results. The network also successfully determined the most accurate release profiles under specific formulation parameters. The simulated results showed a high correlation with the real data in this study. Furthermore, a new method was proposed in order to predict the burst release point in Poly Lactic-co-Glycolic Acid (PLGA) based drug delivery systems. This paper reveals that the mathematical modeling of novel drug delivery systems not only significantly decreases time and cost, but also facilitates the design of new pharmaceutical formulations. |
| Starting Page | 1 |
| Ending Page | 6 |
| File Size | 1123034 |
| Page Count | 6 |
| File Format | |
| ISBN | 9781479930999 |
| ISSN | 08407789 |
| e-ISBN | 9781479931019 |
| DOI | 10.1109/CCECE.2014.6901020 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2014-05-04 |
| Publisher Place | Canada |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Drugs Polymers Drug delivery Mathematical model Artificial neural networks Sensitivity Additives Neural Networks Modeling Drug Delivery Systems |
| Content Type | Text |
| Resource Type | Article |
| Subject | Electrical and Electronic Engineering Hardware and Architecture |
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