NDLI: Partial sparse canonical correlation analysis (PSCCA) for population studies in medical imaging

Content Provider	IEEE Xplore Digital Library
Author	Dhillon, P.S. Avants, B. Ungar, L. Gee, J.C.
Copyright Year	2012
Description	Author affiliation: Department of Radiology, University of Pennsylvania, Philadelphia, PA U.S.A (Avants, B.; Gee, J.C.) \|\| Department of Computer & Information Science, University of Pennsylvania, Philadelphia, PA U.S.A (Dhillon, P.S.; Ungar, L.)
Abstract	We propose a new multivariate method, partial sparse canonical correlation analysis (PSCCA), for computing the statistical comparisons needed by population studies in medical imaging. PSCCA is a multivariate generalization of linear regression that allows one to statistically parameterize imaging studies in terms of multiple views of the population (e.g., the full collection of measurements taken from an image set along with batteries of cognitive or genetic data) while controlling for nuisance variables. This paper develops the theory of PSCCA, provides an algorithm and illustrates PSCCA performance on both simulated and real datasets. We show, as a first application and evaluation of this new methodology, that PSCCA can improve detection power over mass univariate approaches while retaining the interpretability and biological plausibility of the estimated effects. We also discuss the strengths, limitations and future potential of this methodology.
Starting Page	1132
Ending Page	1135
File Size	304880
Page Count	4
File Format	PDF
ISBN	9781457718571
ISSN	19457928
e-ISBN	9781457718588
DOI	10.1109/ISBI.2012.6235759
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2012-05-02
Publisher Place	Spain
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Correlation Vectors Standards Sparse matrices Biomedical imaging Neuroimaging Spectral Methods Multivariate modeling Medical Imaging
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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