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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Chayer, B. de Guise, J.A. Cloutier, G. |
| Copyright Year | 2008 |
| Description | Author affiliation: Lab. of biorheology & Med. Ultrasonics, Univ. of Montreal Hosp. Res. Center, Montreal, QC (Chayer, B.) |
| Abstract | The aim of this study was to evaluate the effect of the depth of correlation (DOC) on the cross-correlation method (CC) applied to microcirculatory blood flow in vitro. The cross-correlation algorithm was optimized to compute red blood cell velocity profiles in tube flow. Flow rates, estimated by computing the circular integral of mean velocity profiles, were compared with calibrated pump flows for different focus planes of the microscope and different flow rates. Results show a mean flow underestimation of 2.8 plusmn 5% for all positions of the focus plane inside the tube diameter, highlighting the non-negligible DOC effect when CC is applied to study blood microcirculation. An underestimation of 1% was found with an optimal focus plane. To conclude, flow rate estimation in microcirculatory blood flow can be accurate if the DOC effect is properly compensated for by the CC flow estimation method. |
| Starting Page | 1359 |
| Ending Page | 1362 |
| File Size | 488320 |
| Page Count | 4 |
| File Format | |
| ISBN | 9781424420025 |
| DOI | 10.1109/ISBI.2008.4541257 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2008-05-14 |
| Publisher Place | France |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Blood flow Fluid flow measurement Glass Microchannel Microscopy Red blood cells Focusing Laboratories Biomedical imaging Hospitals microvessels red blood cells out-of-focus microscopy intravital microscopy blood flow estimation |
| Content Type | Text |
| Resource Type | Article |
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