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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Lathia, J.D. Le, N.T. El-Sherif, D. Forsberg, F. Jin-Bin Liu Merton, D.A. Shimizu, M. Goldberg, B.B. Wheatley, M.A. |
| Copyright Year | 2003 |
| Description | Author affiliation: Sch. of Biomed. Eng., Sci. & Health Syst., Drexel Univ., Philadelphia, PA, USA (Lathia, J.D.; Le, N.T.; El-Sherif, D.) |
| Abstract | Polymer composition, the ratio of lactic acid (LA) to glycolic acid (GA), was evaluated for its contribution to the acoustic enhancement of a poly (co-lactic-glycolic) acid (PLGA) ultrasound contrast agent. Contrast agents were prepared from four different polymer compositions (LA:GA): 100:0, 85:15, 75:25, 50:50 and tested in vivo. The results indicate that all contrast agents perform well in vivo but the 50:50, which had the shortest usable life-time. The performance of the contrast agents was dependent on the ratio of LA to GA and should be considered in the design of polymeric contrast agents. |
| Sponsorship | Schering Plough Becton Dickinson Boston Scientific Reva |
| Starting Page | 323 |
| Ending Page | 324 |
| File Size | 150711 |
| Page Count | 2 |
| File Format | |
| ISBN | 0780377672 |
| DOI | 10.1109/NEBC.2003.1216126 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2003-03-22 |
| Publisher Place | USA |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Polymers In vivo Ultrasonic imaging Rabbits Degradation Biomedical engineering Chemical engineering Biomedical acoustics Acoustic testing System testing |
| Content Type | Text |
| Resource Type | Article |
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