NDLI: Differentiation Between Analyte Adsorption and Homogenous Index Sensing in WGM Biodetection

Content Provider	IEEE Xplore Digital Library
Author	Charlebois, M. Paquet, A. Verret, L.S. Boissinot, K. Boissinot, M. Bergeron, M.G. Allen, C.N.
Copyright Year	2001
Abstract	We propose new parameters to characterize a whispering gallery mode spectrum, which can be regarded as reliable independent biodetection indicators for an instantaneous microsphere's spectrum. With these parameters, since there is no need for spectral comparison to an analyte-free reference, three-dimensional stirring of fluorescent microspheres in fluidic setup is allowed. Through an analysis of fluorescent microspheres in the presence of bacterial spores, we found five insightful quantitative independent parameters for biodetection. Unveiled by this analysis, we demonstrate the possibility to discriminate between analyte presence and homogeneous variation of the solution's refractive index.
Sponsorship	IEEE Sensors Council
Starting Page	229
Ending Page	233
Page Count	5
File Size	525883
File Format	PDF
ISSN	1530437X
Volume Number	13
Issue Number	1
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2013-01-01
Publisher Place	U.S.A.
Access Restriction	One Nation One Subscription (ONOS)
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Refractive index Fluorescence Whispering gallery modes Biosensors Reliability Monitoring Biomedical optical imaging whispering gallery modes (WGM) detection algorithms IMARI
Content Type	Text
Resource Type	Article
Subject	Instrumentation Electrical and Electronic Engineering

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