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The evolution of energy-transducing systems. studies with an extremely halophilic archaebacterium (Document No: 19940020334)
| Content Provider | NASA Technical Reports Server (NTRS) |
|---|---|
| Author | Stan-Lotter, Helga |
| Copyright Year | 1992 |
| Description | The F-type ATPases are found in remarkably similar versions in the energy-transducing membranes of eubacteria, chloroplasts, and mitochondria. Thus, it is likely that they have originated early in the evolution of life, which is consistent with their function as key enzymes of cellular metabolism. The archaebacteria are a group of microorganisms which, as shown by molecular sequencing and biochemical data, have diverged early from the main line of prokaryotic evolution. From studies of members of all three major groups of archaebacteria - the halophiles, methanogens, and thermoacidophiles - it emerged that they possess a membrane ATPase which differs from the F-ATPases. The goal of this project was a comparison of the ATPase from the halophilic archaebacterium Halobacterium saccharovorum with the well-characterized F-type ATPases on the molecular level. Amino acid sequences of critical regions of the enzyme were to be determined, as well as immunoreactions of single subunits in the search for common epitopes. The results were expected to allow a decision about the nature of archaebacterial ATPases, their classification as one of the known or, alternatively, novel enzyme complexes, and possibly deduction of events during the early evolution of energy-transducing systems. |
| File Size | 537819 |
| Page Count | 11 |
| File Format | |
| Alternate Webpage(s) | http://archive.org/details/NASA_NTRS_Archive_19940020334 |
| Archival Resource Key | ark:/13960/t1fj7ck9s |
| Language | English |
| Publisher Date | 1992-08-01 |
| Access Restriction | Open |
| Subject Keyword | Enzymes Classifications Enzyme Activity Archaebacteria Prokaryotes Biological Evolution Cell Membranes Biology Bacteria Amino Acids Sequencing Adenosine Triphosphate Ntrs Nasa Technical Reports ServerĀ (ntrs) Nasa Technical Reports Server Aerodynamics Aircraft Aerospace Engineering Aerospace Aeronautic Space Science |
| Content Type | Text |
| Resource Type | Technical Report |