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| Content Provider | The American Society of Mechanical Engineers (ASME) Digital Collection |
|---|---|
| Author | David, C. Lin David, I. Shreiber Emilios, K. Dimitriadis Horkay, Ferenc |
| Copyright Year | 2008 |
| Abstract | The use of micro and nanoindentation to map the elasticity of cartilage chondrocytes and extracellular matrix has been driven by the desire to understand the changes in microstructure and micromechanical properties of the tissue associated with development and with diseases such as osteoarthritis. Advances in atomic force microscopy (AFM) have facilitated application of the technique to soft tissues, allowing the concurrent imaging and mechanical probing of minute sample regions at high resolution. Examples of the capabilities of the AFM in studying cartilage biomechanics include its use in investigating changes in the elastic properties of the articular surface during development [1], comparing the dynamic elastic response at the microscale and the nanoscale [2], and measuring the elastic moduli of different zones [3]. |
| Sponsorship | Bioengineering Division |
| Starting Page | 1069 |
| Ending Page | 1070 |
| Page Count | 2 |
| File Format | |
| ISBN | 9780791843215 |
| DOI | 10.1115/SBC2008-191631 |
| Volume Number | ASME 2008 Summer Bioengineering Conference, Parts A and B |
| Conference Proceedings | ASME 2008 Summer Bioengineering Conference |
| Language | English |
| Publisher Date | 2008-06-25 |
| Publisher Place | Marco Island, Florida, USA |
| Access Restriction | Subscribed |
| Subject Keyword | Atomic force microscopy Elastic moduli Biological tissues Microscale devices Nanoindentation Elasticity Nanoscale phenomena Diseases Soft tissues Biomechanics Cartilage Imaging Chondrocytes Resolution (optics) Osteoarthritis |
| Content Type | Text |
| Resource Type | Article |
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