NDLI: Unilateral versus bilateral upper limb training after stroke: the Upper Limb Training After Stroke clinical trial.

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Unilateral versus bilateral upper limb training after stroke: the Upper Limb Training After Stroke clinical trial.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Nienhuys, Kirsten N. Peper, C. Lieke E. Zijp, Nienke I. Kwakkel, Gert Van Delden, A. Lex E. Q. Beek, Peter J.
Description	Country affiliation: Netherlands Author Affiliation: van Delden AL ( Faculty of Human Movement Sciences, VU University Amsterdam, Amsterdam, The Netherlands. l.van.delden@vu.nl)
Abstract	BACKGROUND AND PURPOSE: Unilateral and bilateral training protocols for upper limb rehabilitation after stroke represent conceptually contrasting approaches with the same ultimate goal. In a randomized controlled trial, we compared the merits of modified constraint-induced movement therapy, modified bilateral arm training with rhythmic auditory cueing, and a dose-matched conventional treatment. Modified constraint-induced movement therapy and modified bilateral arm training with rhythmic auditory cueing targeted wrist and finger extensors, given their importance for functional recovery. We hypothesized that modified constraint-induced movement therapy and modified bilateral arm training with rhythmic auditory cueing are superior to dose-matched conventional treatment. METHODS: Sixty patients, between 1 to 6 months after stroke, were randomized over 3 intervention groups. The primary outcome measure was the Action Research Arm test, which was conducted before, directly after, and 6 weeks after intervention. RESULTS: Although all groups demonstrated significant improvement on the Action Research Arm test after intervention, which persisted at 6 weeks follow-up, no significant differences in change scores on the Action Research Arm test were found between groups postintervention and at follow-up. CONCLUSIONS: Modified constraint-induced movement therapy and modified bilateral arm training with rhythmic auditory cueing are not superior to dose-matched conventional treatment or each other in improving upper limb motor function 1 to 6 months after stroke. CLINICAL TRIAL REGISTRATION URL: http://www.trialregister.nl. Unique identifier: NTR1665.
ISSN	00392499
e-ISSN	15244628
Journal	Stroke
Issue Number	9
Volume Number	44
Language	English
Publisher	Lippincott Williams & Wilkins (on behalf of the American Heart Association)
Publisher Date	2013-09-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Exercise Therapy Upper Extremity Physiopathology Acoustic Stimulation Utilization Clinical Protocols Cues Fingers Recovery Of Function Physiology Wrist Comparative Study Randomized Controlled Trial Research Support, Non-u.s. Gov't Discipline Cardiology
Content Type	Text
Resource Type	Article
Subject	Cardiology and Cardiovascular Medicine Neuroscience Advanced and Specialized Nursing Neurology (clinical)

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