NDLI: Open-frame system for single-molecule microscopy.

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Contributed review: quantum cascade laser based photoacoustic detection of explosives.

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Time-of-flight Extreme Environment Diffractometer at the Helmholtz-Zentrum Berlin.

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Open-frame system for single-molecule microscopy.

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Note: proton microbeam formation with continuously variable kinetic energy using a compact system for three-dimensional proton beam writing.

Note: fast neutron efficiency in CR-39 nuclear track detectors.

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Open-frame system for single-molecule microscopy.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Talbot, Richard Leslie, Sabrina R. Berard, Daniel Michaud, Francois Henkin, Gil Tarling, Matthew Arsenault, Adriel McFaul, Christopher M. J. Scott, Shane Leith, Jason S.
Description	Country affiliation: Canada Author Affiliation: Arsenault A ( Department of Physics, McGill University, Montreal, Quebec H3A 2T8, Canada.); Leith JS ( Department of Physics, McGill University, Montreal, Quebec H3A 2T8, Canada.); Henkin G ( Department of Physics, McGill University, Montreal, Quebec H3A 2T8, Canada.); McFaul CM ( Department of Physics, McGill University, Montreal, Quebec H3A 2T8, Canada.); Tarling M ( Department of Physics, McGill University, Montreal, Quebec H3A 2T8, Canada.); Talbot R ( Department of Physics, McGill University, Montreal, Quebec H3A 2T8, Canada.); Berard D ( Department of Physics, McGill University, Montreal, Quebec H3A 2T8, Canada.); Michaud F ( Department of Physics, McGill University, Montreal, Quebec H3A 2T8, Canada.); Scott S ( Department of Physics, McGill University, Montreal, Quebec H3A 2T8, Canada.); Leslie SR ( Department of Physics, McGill University, Montreal, Quebec H3A 2T8, Canada.)
Abstract	We present the design and construction of a versatile, open frame inverted microscope system for wide-field fluorescence and single molecule imaging. The microscope chassis and modular design allow for customization, expansion, and experimental flexibility. We present two components which are included with the microscope which extend its basic capabilities and together create a powerful microscopy system: A Convex Lens-induced Confinement device provides the system with single-molecule imaging capabilities, and a two-color imaging system provides the option of imaging multiple molecular species simultaneously. The flexibility of the open-framed chassis combined with accessible single-molecule, multi-species imaging technology supports a wide range of new measurements in the health, nanotechnology, and materials science research sectors.
ISSN	00346748
Issue Number	3
Volume Number	86
e-ISSN	10897623
Journal	Review of Scientific Instruments
Language	English
Publisher	American Institute of Physics
Publisher Date	2015-03-01
Publisher Place	United States
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Microscopy Instrumentation Molecular Imaging Optical Imaging Bacteriophage Lambda Genetics Dna, Viral Chemistry Diffusion Equipment Design Fluorescence Resonance Energy Transfer Fluorescent Dyes Lasers Oligonucleotides Photobleaching Polyethylene Glycols Solutions Streptavidin Journal Article Research Support, Non-u.s. Gov't Discipline Physics Discipline Chemistry
Content Type	Text
Resource Type	Article
Subject	Medicine Instrumentation

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