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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | McNabb, Scott J. N. Navin, Thomas R. Braden, Christopher R. |
| Spatial Coverage | United States |
| Description | Country affiliation: United States Author Affiliation: McNabb SJ ( Centers for Disesase Control and Prevention, Atlanta, GA 30333, USA. sym3@cdc.gov) |
| Abstract | DNA fingerprinting of Mycobacterium tuberculosis--a relatively new laboratory technique--offers promise as a powerful aid in the prevention and control of tuberculosis (TB). Established in 1996 by the Centers for Disease Control and Prevention (CDC), the National Tuberculosis Genotyping and Surveillance Network was a 5-year prospective, population-based study of DNA fingerprinting conducted from 1996 to 2000. The data from this study suggest multiple molecular epidemiologic and program management uses for DNA fingerprinting in TB public health practice. From these data, we also gain a clearer understanding of the overall diversity of M. tuberculosis strains as well as the presence of endemic strains in the United States. We summarize the key findings and the impact that DNA fingerprinting may have on future approaches to TB control. Although challenges and limitations to the use of DNA fingerprinting exist, the widespread implementation of the technique into routine TB prevention and control practices appears scientifically justified. |
| ISSN | 10806040 |
| e-ISSN | 10806059 |
| Journal | Emerging Infectious Diseases |
| Issue Number | 11 |
| Volume Number | 8 |
| Language | English |
| Publisher | Centers for Disease Control and Prevention |
| Publisher Date | 2002-11-01 |
| Publisher Place | United States |
| Access Restriction | Open |
| Subject Keyword | Dna Fingerprinting Mycobacterium Tuberculosis Genetics Tuberculosis Diagnosis Microbiology Centers For Disease Control And Prevention (u.s.) Organization & Administration Cluster Analysis Utilization Diagnostic Errors Disease Outbreaks Equipment Contamination Genetic Variation Laboratories Molecular Epidemiology Risk Factors Epidemiology Transmission Research Support, Non-u.s. Gov't Research Support, U.s. Gov't, Non-p.h.s. Discipline Infectious Diseases |
| Content Type | Text |
| Resource Type | Article |
| Subject | Infectious Diseases Epidemiology Microbiology (medical) |
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