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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Kim, Sang Nyon Naik, Rajesh R. Auvil, Tyler Liu, Jinny Slocik, Joseph M. Goldman, Ellen R. |
| Description | Country affiliation: United States Author Affiliation: Slocik JM ( Nanostructured & Biological Materials Branch, Materials & Manufacturing Directorate, Air Force Research Lab, Wright-Patterson Air Force Base, OH 45433, USA.) |
| Abstract | The diversity of biomolecules enables materials to be synthesized at ambient conditions into complex shapes and structures while affording improved control over nanoparticle synthesis, structures, properties, and functionality. Also, biomolecules can impart recognition and sensing capabilities to metal nanoparticles. Here, llama single domain antibodies selected towards the beta-subunit of cholera toxin were used to template the synthesis of gold nanoparticles and subsequently assembled onto electrodes via dielectrophoresis. These assemblies were then tested for the detection of cholera toxin via changes in the conductance of antibody coated gold nanoparticles. |
| ISSN | 09565663 |
| Issue Number | 8 |
| Volume Number | 25 |
| e-ISSN | 18734235 |
| Journal | Biosensors and Bioelectronics |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2010-04-15 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Antibodies, Bacterial Chemistry Biosensing Techniques Instrumentation Cholera Toxin Analysis Conductometry Immunoassay Nanoparticles Nanotechnology Immunology Electric Impedance Equipment Design Equipment Failure Analysis Ultrastructure Protein Structure, Tertiary Reproducibility Of Results Sensitivity And Specificity Evaluation Studies Journal Article Research Support, U.s. Gov't, Non-p.h.s. Discipline Biotechnology |
| Content Type | Text |
| Resource Type | Article |
| Subject | Nanoscience and Nanotechnology Medicine Biophysics Biomedical Engineering Biotechnology Electrochemistry |
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