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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Takenaka, Tomohiro Yang, Yangyang Hidaka, Kumi Endo, Masayuki Namba, Keiichi Kato, Takayuki Suzuki, Yuki Emura, Tomoko Sugiyama, Hiroshi Miyata, Tomoko |
| Description | Author Affiliation: Takenaka T ( Department of Chemistry, Graduate School of Science, Kyoto University, Kitashirakawa-oiwakecho, Sakyo-ku, Kyoto 606-8502 (Japan).) |
| Abstract | A photofunctionalized square bipyramidal DNA nanocapsule (NC) was designed and prepared for the creation of a nanomaterial carrier. Photocontrollable open/close system and toehold system were introduced into the NC for the inclusion and release of a gold nanoparticle (AuNP) by photoirradiation and strand displacement. The reversible open and closed states were examined by gel electrophoresis and atomic force microscopy (AFM), and the open behavior was directly observed by high-speed AFM. The encapsulation of the DNA-modified AuNP within the NC was carried out by hybridization of a specific DNA strand (capture strand), and the release of the AuNP was examined by addition of toehold-containing complementary DNA strand (release strand). The release of the AuNP from the NC was achieved by the opening of the NC and subsequent strand displacement. |
| ISSN | 09476539 |
| e-ISSN | 15213765 |
| Journal | Chemistry - A European Journal |
| Issue Number | 46 |
| Volume Number | 20 |
| Language | English |
| Publisher | Wiley-VCH;ChemPubSoc Europe |
| Publisher Date | 2014-11-10 |
| Publisher Place | Germany |
| Access Restriction | Open |
| Subject Keyword | DNA Chemistry Delayed-Action Preparations Administration & Dosage Metal Nanoparticles Nanocapsules Ultrastructure Nucleic Acid Conformation Photochemical Processes Research Support, Non-U.S. Gov't |
| Content Type | Text |
| Resource Type | Article |
| Subject | Organic Chemistry Catalysis |
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