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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Egido, Jesus Burkly, Linda C. Ruiz-ortega, Marta Sanz, Ana Belen Nair, Viji Sanchez-niño, Maria Dolores Selgas, Rafael Hodgin, Jeffrey B. Mezzano, Sergio Fernandez-fernandez, Beatriz Kretzler, Matthias Poveda, Jonay Carrasco, Susana Ortiz, Alberto |
| Description | Author Affiliation: Sanchez-Niño MD ( Servicio de Nefrologia, IdiPAZ, Madrid 28046, Spain.) |
| Abstract | Non-proliferative proteinuric diseases are the most common primary glomerular disorders causing end-stage renal disease. These disorders may associate low level glomerular inflammation and podocyte expression of inflammatory mediators. However, the factors regulating podocyte expression of inflammatory mediators in vivo in non-immune disorders are poorly understood. We have now explored the regulation and role of TWEAK receptor Fn14 in mediating glomerular inflammation in cultured podocytes and in experimental and human non-immune proteinuria. |
| ISSN | 00063002 |
| Journal | Biochimica et Biophysica Acta (BBA) - Reviews on Cancer |
| Issue Number | 12 |
| Volume Number | 1832 |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2013-12-01 |
| Publisher Place | Netherlands |
| Access Restriction | Open |
| Subject Keyword | Inflammation Metabolism Kidney Diseases Kidney Glomerulus Podocytes Proteinuria Receptors, Tumor Necrosis Factor Physiology Adolescent Animals Biological Markers Blotting, Southwestern Blotting, Western Case-Control Studies Cells, Cultured Chemokine CCL2 Genetics Cytokines Electrophoretic Mobility Shift Assay Fluorescent Antibody Technique Gene Expression Profiling Immunoenzyme Techniques Pathology Mice Mice, Inbred C57BL Mice, Knockout NF-kappa B Oligonucleotide Array Sequence Analysis RNA, Messenger Real-Time Polymerase Chain Reaction Reverse Transcriptase Polymerase Chain Reaction Tumor Necrosis Factors Comparative Study Research Support, Non-U.S. Gov't Biochemistry |
| Content Type | Text |
| Resource Type | Article |
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