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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Sarkar, Pamela Ibitoye, Richard Tolulope Promnitz, Douglas Anthony |
| Description | Author Affiliation: Sarkar P ( Ipswich Hospital NHS Trust, Ipswich, Suffolk, UK. pam524sarkar@hotmail.com) |
| Abstract | A lady in her 70s with a background of multiple sclerosis (MS) and late-onset asthma was admitted with a 2-week history of cough and shortness of breath, progressive right-sided weakness and functional decline. Investigation revealed eosinophilia, elevated myeloperoxidase antineutrophil cytoplasmic antibody, CT sinuses showed long-standing inflammatory changes consistent with sinonasal polyposis and MRI head showed lesions consistent with vasculitis. She then developed left-sided weakness and increased wheeze. Review of her case notes demonstrated that, the eosinophilia was long-standing, her asthma was severe and steroid-dependent, and her neurologic syndrome was atypical for MS. Intravenous methylprednisolone then cyclophosphamide were administered. She demonstrated remarkable improvement, becoming more alert, with improvement in left-sided weakness. A diagnosis of Churg-Strauss syndrome was established. She was discharged to a nursing home with outpatient rheumatology follow-up. The diagnosis of MS was revisited. |
| e-ISSN | 1757790X |
| Journal | BMJ Case Reports |
| Volume Number | 2011 |
| Language | English |
| Publisher | BMJ Publishing Group Ltd. |
| Publisher Place | Great Britain (UK) |
| Access Restriction | Open |
| Subject Keyword | Churg-Strauss Syndrome Diagnosis Anti-Inflammatory Agents Therapeutic Use Drug Therapy Cyclophosphamide Diagnosis, Differential Immunosuppressive Agents Methylprednisolone Multiple Sclerosis Multidisciplinary |
| Content Type | Text |
| Resource Type | Article |
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