NDLI: Molecular signals for initiating protein synthesis in organ hypertrophy.

Please wait, while we are loading the content...

Year: 2017 Volume: 114

Year: 2016 Volume: 113

Year: 2015 Volume: 112

Year: 2014 Volume: 111

Year: 2013 Volume: 110

Year: 2012 Volume: 109

Year: 2011 Volume: 108

Year: 2010 Volume: 107

Year: 2009 Volume: 106

Year: 2008 Volume: 105

Year: 2007 Volume: 104

Year: 2006 Volume: 103

Year: 2005 Volume: 102

Year: 2004 Volume: 101

Year: 2003 Volume: 100

Year: 2002 Volume: 99

Year: 2001 Volume: 98

Year: 2000 Volume: 97

Year: 1999 Volume: 96

Year: 1998 Volume: 95

Year: 1997 Volume: 94

Year: 1996 Volume: 93

Year: 1995 Volume: 92

Year: 1994 Volume: 91

Year: 1993 Volume: 90

Year: 1992 Volume: 89

Year: 1991 Volume: 88

Year: 1990 Volume: 87

Year: 1989 Volume: 86

Year: 1988 Volume: 85

Year: 1987 Volume: 84

Year: 1986 Volume: 83

Year: 1985 Volume: 82

Year: 1984 Volume: 81

Year: 1983 Volume: 80

Year: 1982 Volume: 79

Year: 1981 Volume: 78

Year: 1980 Volume: 77

Year: 1979 Volume: 76

Year: 1979 Volume: 76 Issue: 12

Year: 1979 Volume: 76 Issue: 11

Year: 1979 Volume: 76 Issue: 10

Year: 1979 Volume: 76 Issue: 9

Year: 1979 Volume: 76 Issue: 8

Year: 1979 Volume: 76 Issue: 7

Year: 1979 Volume: 76 Issue: 6

Year: 1979 Volume: 76 Issue: 5

A genetic approach to analysis of transposons.

Reevaluation of level of genic heterozygosity in natural population of Drosophila melanogaster by two-dimensional electrophoresis.

Mutation generating a fragment of the major heat shock-inducible polypeptide in Drosophila melanogaster.

Plasmin-mediated proteolysis of casein in bovine milk.

Down syndrome: gene dosage at the transcriptional level in skin fibroblasts.

Molecular signals for initiating protein synthesis in organ hypertrophy.

Codon-anticodon interaction at the ribosomal P (peptidyl-tRNA)site.

Corticotropin and beta-endorphin: construction and analysis of recombinant DNA complementary to mRNA for the common precursor.

Structural studies on oncornavirus-related sequences in chicken genomic DNA: two-step analyses of EcoRI and Bgl I restriction digests and tentative mapping of a ubiquitous endogenous provirus digests and tentative mapping of a ubiquitous endogenous provirus.

Synthesis and use of 8-azidoguanosine 3',5'-cyclic monophosphate as photoaffinity label for cyclic GMP-dependent protein kinase.

Adenine nucleotide storage and secretion in platelets as studied by 31P nuclear magnetic resonance.

Preferential digestion of basement membrane collagen by an enzyme derived from a metastatic murine tumor.

Rate and equilibrium constants for binding of apo-E HDLc (a cholesterol-induced lipoprotein) and low density lipoproteins to human fibroblasts: evidence for multiple receptor binding of apo-E HDLc.

Detection by complementation of defective or uninducible (herpes simplex type 1) virus genomes latent in human ganglia.

Detection of a transformation-related antigen in chemically induced sarcomas and other transformed cells of the mouse.

Biochemical basis for differential deoxyadenosine toxicity to T and B lymphoblasts: role for 5'-nucleotidase.

Lymphoma development in mice and humans: diversity of initiation is followed by convergent cytogenetic evolution.

S-adenosylhomocysteine toxicity in normal and adenosine kinase-deficient lymphoblasts of human origin.

Integration of different sarcoma virus genomes into host DNA: evidence against tandem arrangement and for shared integration sites.

Ca2+ and cyclic AMP regulate phosphorylation of same two membrane-associated proteins specific to nerve tissue.

Geometric and electronic structure of oxyhemocyanin: spectral and chemical correlations to met apo, half met, met, and dimer active sites.

In situ phosphorylation of the alpha subunit of eukaryotic initiation factor 2 in reticulocyte lysates inhibited by heme deficiency, double-stranded RNA, oxidized glutathione, or the heme-regulated protein kinase.

Albumin microspheres as carrier of an inhibitor of leukocyte elastase: potential therapeutic agent for emphysema.

Reaction of nucleosome DNA with dimethyl sulfate.

Further studies on the mode of action of the heme-controlled translational inhibitor: stimulating protein acts at level of binary complex formation.

Methods for identifying proteins by using partial sequences.

Mechanisms and prevention of trifluoroacetylation in solid-phase peptide synthesis.

Activation of phenotypic expression of human globin genes from nonerythroid cells by chromosome-dependent transfer to tetraploid mouse erythroleukemia cells.

Histone 1 is proximal to histone 2A and to A24.

Organization of a hybrid between phage f1 and plasmid pSC101.

Effect of Cibacron blue F3GA on oligonucleotide binding site of estradiol--receptor complexes of mouse uterine cytosol.

Cellular retinol-binding protein allows specific interaction of retinol with the nucleus in vitro.

Distinct single-copy sequence sets in sea urchin nuclear RNAs.

Inhibition of human neuroblastoma DNA polymerase activities by plant lectins and toxins.

Structure-independent nucleotide sequence analysis.

Steady-state coupling of four membrane systems in mitochondrial oxidative phosphorylation.

Thermotropic behavior of some fluorodimyristoylphosphatidylcholines.

The ovalbumin gene: cloning and molecular organization of the entire natural gene.

Cell-free translation of the mRNAs for the heavy and light chains of HLA-A and HLA-B antigens.

Macrophage response to concanavalin A: effect of surface crosslinking on the electrophoretic mobility distribution.

The rate of access to the organic ligand-binding region of serum albumin is entropy controlled.

Complexity transmission during replication.

Diamagnetic anisotropy of the peptide group.

Upper surfaces of epithelial sheets and of fluid lipid films are nonadhesive for platelets.

Appearance in confluent vascular endothelial cell monolayers of a specific cell surface protein (CSP-60) not detected in actively growing endothelial cells or in cell types growing in multiple layers.

Functional roles of DNA polymerases beta and gamma.

Villin: the major microfilament-associated protein of the intestinal microvillus.

Direct demonstration of binding of a lysosomal enzyme, alpha-L-iduronidase, to receptors on cultured fibroblasts.

Syndeins: the spectrin-binding protein(s) of the human erythrocyte membrane.

Actin polymerization induced by a motility-related high-affinity cytochalasin binding complex from human erythrocyte membrane.

Sodium-induced calcium release from mitochondria in brown adipose tissue.

Partial deletion of beta-globin gene DNA in certain patients with beta 0-thalassemia.

Pregnant mice are not primed but can be primed to fetal alloantigens.

Serum iron levels and response to hepatitis B virus.

Release and distribution of [3H]norepinephrine in nonpigmented and pigmented rabbit iris.

A sciatic nerve protein has a trophic effect on development and maintenance of skeletal muscle cells in culture.

Induction of prostaglandin E synthesis in normal and neoplastic macrophages: role for colony-stimulating factor(s) distinct from effects on myeloid progenitor cell proliferation.

Immunosuppression by Friend leukemia virus is H-2 restricted by alloreactive T lymphocytes.

Biochemical basis for the enhanced toxicity of deoxyribonucleosides toward malignant human T cell lines.

$H^{+}/site,$ charge/site, and ATP/site ratios in mitochondrial electron transport

Cellular energy metabolism, trans-plasma and trans-mitochondrial membrane potentials, and pH gradients in mouse neuroblastoma.

Translocation of glutathione from lymphoid cells that have markedly different gamma-glutamyl transpeptidase activities.

Antibodies raised against purified beta-adrenergic receptors specifically bind beta-adrenergic ligands.

Genetic variation and relative catalytic efficiencies: lactate dehydrogenase B allozymes of Fundulus heteroclitus.

Neuroactive drugs inhibit trypsin and outer membrane protein processing in Escherichia coli K-12.

Arachidonic acid metabolism in polymorphonuclear leukocytes: effects of ionophore A23187.

Glutathione-dependent hydrogen donor system for calf thymus ribonucleoside-diphosphate reductase.

Cloning in Escherichia coli and physical structure of hepatitis B virion DNA.

Interaction of the cheC and cheZ gene products is required for chemotactic behavior in Escherichia coli.

Septum formation, cell division, and sporulation in mutants of yeast deficient in proteinase B.

Immunological tolerance: high-dose antigen-induced suppressor cells from tolerant animals inactivate antigen-presenting macrophages.

Fine specificity of antibodies to poly(Glu60Ala30Tyr10) produced by hybrid cell lines.

Human breast carcinoma antigen is immunologically related to the polypeptide of the group-specific glycoprotein of mouse mammary tumor virus.

Year: 1979 Volume: 76 Issue: 4

Year: 1979 Volume: 76 Issue: 3

Year: 1979 Volume: 76 Issue: 2

Year: 1979 Volume: 76 Issue: 1

Year: 1978 Volume: 75

Year: 1977 Volume: 74

Year: 1976 Volume: 73

Year: 1975 Volume: 72

Year: 1974 Volume: 71

Year: 1973 Volume: 70

Year: 1972 Volume: 69

Year: 1971 Volume: 68

Year: 1970 Volume: 67

Year: 1970 Volume: 66

Year: 1970 Volume: 65

Year: 1969 Volume: 64

Year: 1969 Volume: 63

Year: 1969 Volume: 62

Year: 1968 Volume: 61

Year: 1968 Volume: 60

Year: 1968 Volume: 59

Year: 1967 Volume: 58

Year: 1967 Volume: 57

Year: 1966 Volume: 56

Year: 1966 Volume: 55

Molecular signals for initiating protein synthesis in organ hypertrophy.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Hammond, G. L. Wieben, E. Markert, C. L.
Abstract	When chronically provoked to increased physiologic activity, organs increase in mass through augmented protein protein synthesis. This process of compensatory hypertrophy can involve cell division as well as cell growth. To test for molecules that might regulate organ size, by inducing hypertrophy, we performed a series of experiments using isolated, perfused, canine hearts in which the left ventricle was beating but performed no work. Hypertrophying hearts and kidneys as well as normal control organs were extracted and the extracts were perfused through isolated heart preparations. Before and after perfusion, RNA was extracted from fragments of the isolated hearts and translated in cell-free media containing [35S]methionine. Incorporation of methionine into protein was measured by liquid scintillation spectrometry. When perfused through normal hearts, extracts from hypertrophying heart and kidney were able to increase greatly the translational ability of RNA extracted from the normal hearts; corresponding perfusates from nonhypertrophying hearts and kidneys had no effect. Our results indicate that molecules that initiate hypertrophic organ growth are extractable, are generated by the cells of the organ under stress, and are probably similar in heart and kidney and perhaps in many other organs as well.
ISSN	00278424
e-ISSN	10916490
Journal	Proceedings of the National Academy of Sciences of the United States of America
Issue Number	5
Volume Number	76
Language	English
Publisher	National Academy of Sciences
Publisher Date	1979-08-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Cardiomegaly Metabolism Hypertrophy Protein Biosynthesis Animals Blood Kidney Pathology Muscle Proteins Biosynthesis Multidisciplinary
Content Type	Text
Resource Type	Article
Subject	Multidisciplinary

Central Library (ISO-9001:2015 Certified)
Indian Institute of Technology Kharagpur
Kharagpur, West Bengal, India | PIN - 721302

See location in the Map
03222 282435
Mail: support@ndl.gov.in

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in