NDLI: Ubiquitous cell-surface glycoprotein on tumor cells is proliferation-associated receptor for transferrin.

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Opiates inhibit adenylate cyclase by stimulating GTP hydrolysis.

Production and characterization of monoclonal antibodies to soluble rat lung guanylate cyclase.

Distinct high-affinity binding sites for benzomorphan drugs and enkephalin in a neuroblastoma--brain hybrid cell line.

Selection of rat hepatoma cells defective in hormone-regulated production of mouse mammary tumor virus RNA.

Isolation of a taxol-resistant Chinese hamster ovary cell mutant that has an alteration in alpha-tubulin.

Taxol, a microtubule stabilizing agent, blocks the replication of Trypanosoma cruzi.

Introduction by molecular cloning of artifactual inverted sequences at the 5' terminus of the sense strand of bovine parathyroid hormone cDNA.

Characterization of a class of cationic proteins that specifically interact with intermediate filaments.

Platelet-derived growth factor-modulated proteins: constitutive synthesis by a transformed cell line.

Cytoplasmic transfer of the mitogenic response to platelet-derived growth factor.

Novel models for RNA splicing that involve a small nuclear RNA.

Multiple differences between the nucleic acid sequences of the IgG2aa and IgG2ab alleles of the mouse.

Immune response potential to poly(Tyr,Glu)-poly(DLAla)--poly(Lys) of human T cells of different donors.

Production of immunologically active surface antigens of hepatitis B virus by Escherichia coli.

Functional association of idiotypic and I-J determinants on the antigen receptor of suppressor T cells.

Similarities in development of substance P and somatostatin in peripheral sensory neurons: effects of capsaicin and nerve growth factor.

Mechanism for transcriptional action of cyclic AMP in Escherichia coli: entry into DNA to disrupt DNA secondary structure.

Discrete-length repeated sequences in eukaryotic genomes.

Solubilization of human platelet alpha-adrenergic receptors: evidence that agonist occupancy of the receptor stabilizes receptor--effector interactions.

Recombinant bacteriophages containing the integrated transforming provirus of Gardner--Arnstein feline sarcoma virus.

Transposon Tn3 encodes a site-specific recombination system: identification of essential sequences, genes, and actual site of recombination.

Energy-dependent reversal of the cytochrome oxidase reaction.

New segment-coupling method for peptide synthesis in aqueous solution: application to synthesis of human [Gly17]-beta-endorphin.

Phosphorylation of ribosomal protein S6 in avian sarcoma virus-transformed chicken embryo fibroblasts.

Novel opiate binding sites selective for benzomorphan drugs.

Site-specific interaction of DNA gyrase with DNA.

Molecular cloning and partial characterization of unintegrated linear DNA from gibbon ape leukemia virus.

A nucleotide change at a splice junction in the human beta-globin gene is associated with beta 0-thalassemia.

Radioimmunochemical measurement of the transferrin receptor in human trophoblast and reticulocyte membranes with a specific anti-receptor antibody.

Rapid purification of a high-affinity plasminogen activator from human blood plasma by specific adsorption on fibrin/Celite.

Sequences of the ssb gene and protein.

Somatomedin receptor of human placenta: solubilization, photolabeling, partial purification, and comparison with insulin receptor.

Characterization of a membrane-associated receptor from bovine liver that binds phosphomannosyl residues of bovine testicular beta-galactosidase.

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Reciprocity or near-reciprocity of highly coupled enzymatic processes at the multidimensional inflection point.

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Proton and hydroxide ion permeability of phospholipid vesicles.

Insulin synthesis in a clonal cell line of simian virus 40-transformed hamster pancreatic beta cells.

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Functional unit of the low density lipoprotein receptor of fibroblasts: a 100,000-dalton structure with multiple binding sites.

Biological activity of cloned retroviral DNA in microinjected cells.

Cyclic AMP: a mitogenic signal for Swiss 3T3 cells.

Temperature-sensitive RNA polymerase mutants of a picornavirus.

Specific transcriptional initiation in vitro on murine type C retrovirus promoters.

Ubiquitous cell-surface glycoprotein on tumor cells is proliferation-associated receptor for transferrin.

Subunit structure of cell surface proteins: disulfide bonding in antigen receptors, Ly-2/3 antigens, and transferrin receptors of murine T and B lymphocytes.

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Evidence against extrapancreatic insulin synthesis.

Contractile activities of structural analogs of leukotrienes C and D: role of the polar substituents.

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Seesaw signal processing in pineal cells: homologous sensitization of adrenergic stimulation of cyclic GMP accompanies homologous desensitization of beta-adrenergic stimulation of cyclic AMP.

Characterization and partial purification of solubilized active opiate receptors from toad brain.

Anatoxin-a interactions with cholinergic synaptic molecules.

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Isolation of two clusters of mouse histone genes.

Isolation and characterization of adult bovine heart muscle chalones.

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Multiple amino acid substitutions between murine gamma 2a heavy chain Fc regions of Ig1a and Ig1b allotypic forms.

Attachment site(s) of retinal in bacteriorhodopsin.

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Pyochelin: novel structure of an iron-chelating growth promoter for Pseudomonas aeruginosa.

Evidence for biochemical and physiological differences between enzyme genotypes in Drosophila melanogaster.

Direct immunoassay for detecting Escherichia coli colonies that contain polypeptides encoded by cloned DNA segments.

Structural analysis of a new B-cell-differentiation antigen associated with products of the I-A subregion of the H-2 complex.

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Mediation of retinal photoisomerization by adduct formation with tris(6,6,7,7,8,8,8-heptafluoro-2,2-dimethyl-3,5-octanedionato)-europium(II).

Stoichiometry and composition of an aminoacyl-tRNA synthetase complex from rat liver.

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Transcription and processing of adenoviral RNA by extracts from HeLa cells.

Initiation of DNA replication at the primary origin of bacteriophage T7 by purified proteins: requirement for T7 RNA polymerase.

Comparison of the proteins of two immunologically distinct intermediate-sized filaments by amino acid sequence analysis: desmin and vimentin.

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Complete amino acid sequence of beta-tubulin from porcine brain.

Sequences of mRNAs derived from genome RNA segment 7 of influenza virus: colinear and interrupted mRNAs code for overlapping proteins.

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Folding units in globular proteins.

Stabilization and the cytoplasmic ground substance in detergent-opened cells and a structural and biochemical analysis of its composition.

Mitogenic effect of alkaline pH on quiescent, serum-starved cells.

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Glia maturation factor promotes contact inhibition in cancer cells.

Tumor-promoting phorbol esters stimulate myelopoiesis and suppress erythropoiesis in cultures of mouse bone marrow cells.

Diffusion of injected macromolecules within the cytoplasm of living cells.

Two-dimensional gel analysis of rat liver nuclear proteins after thyroidectomy and thyroid hormone treatment.

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31P NMR reveals increased intracellular pH after fertilization in Xenopus eggs.

Change in state of phosphorylation of acetylcholine receptor during maturation of the electromotor synapse in Torpedo marmorata electric organ.

Indirect induction of mutagenesis of intact parvovirus H-1 in mammalian cells treated with UV light or with UV-irradiated H-1 or simian virus 40.

Distinct forms of both alpha and beta subunits are present in the human Ia molecular pool.

Specific antibody-dependent interactions between macrophages and lipid haptens in planar lipid monolayers.

Cryoprecipitogogue from normal serum: mechanism for cryoprecipitation of immune complexes.

Platelet factor 4 is chemotactic for neutrophils and monocytes.

Role of cysteine in regulating morphogenesis and mitochondrial activity in the dimorphic fungus Histoplasma capsulatum.

Involvement of small-field horizontal cells in feedback effects on green cones of turtle retina.

Mutant mouse tottering: selective increase of locus ceruleus axons in a defined single-locus mutation.

Inhibition of specific cell-mediated cytotoxicity by monoclonal antibodies to human T cell antigens.

T cells may express multiple activities: specific allohelp, cytolysis, and delayed-type hypersensitivity are expressed by a cloned T-cell line.

Human B-cell alloantigens DC1, MT1, and LB12 are identical to each other but distinct from the HLA-DR antigen.

Purification of guinea pig pH 3 migration inhibitory factor.

Removal of beta subunit of the eukaryotic polypeptide chain initiation factor 2 by limited proteolysis.

Synthetic sites for transcription termination and a functional comparison with tryptophan operon termination sites in vitro.

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Mechanism of action of the lexA gene product.

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Intracellular disruption of rat heart lysosomes by leucine methyl ester: effects on protein degradation.

Localization of the human insulin gene to the distal end of the short arm of chromosome 11.

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Transplacental passage of insulin complexed to antibody.

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Ubiquitous cell-surface glycoprotein on tumor cells is proliferation-associated receptor for transferrin.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Schneider, C. Delia, D. Kemshead, J. Sutherland, R. Newman, R. Greaves, M.
Abstract	A murine monoclonal antibody (OKT9) raised against human leukemic cells binds to a wide variety of leukemia and tumor cell lines and to a minority of leukemia cells taken directly from patients. Fetal thymus and liver are strongly reactive as are some normal, immature hemopoietic cells and activated lymphocytes. Reactivity with OKT9 appears to correlate with proliferation status in both normal and malignant populations. Biochemical analysis indicates that this structure is a approximately equal to 180,000-dalton glycoprotein with two disulfide-bonded subunits of approximately equal to 90,000-daltons. Isolation of the transferrin receptor from a T-cell line (MOLT-4) indicates that it also has a dimeric approximately equal to 180,000-dalton structure. Radio-labeled transferrin bound to its receptors can be specifically precipitated by the monoclonal OKT9, although the latter does not bind transferrin itself, indicating that the antigenic structure defined by this antibody is likely to be the transferrin receptor.
ISSN	00278424
e-ISSN	10916490
Journal	Proceedings of the National Academy of Sciences of the United States of America
Issue Number	7
Volume Number	78
Language	English
Publisher	National Academy of Sciences
Publisher Date	1981-12-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Antigens, Neoplasm Immunology Antigens, Surface Glycoproteins Receptors, Cell Surface T-Lymphocytes Transferrin Metabolism Animals Antibodies, Monoclonal Cell Division Membrane Proteins Mice Receptors, Transferrin Multidisciplinary
Content Type	Text
Resource Type	Article
Subject	Multidisciplinary

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