NDLI: Anti-peptide antibodies detect oncogene-related proteins in urine.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Thompson, A. M. Willems, J. J. Niman, H. L. Wood, C. B. Lerner, R. A. Markman, M. Yu, A. Habib, N. A. Herwig, K. R. Houghten, R. A.
Abstract	Antisera to a number of synthetic peptides predicted from nucleic acid sequences of oncogenes have been used to screen 483 urine samples of cancer patients, pregnant women, and normal controls for the presence of immunologically related proteins. Increased levels of oncogene-related proteins are found during neoplasia and pregnancy. The differential detection of these oncogene-related proteins indicates that panels of monoclonal antibodies may provide a convenient noninvasive means of detecting, classifying, and staging a wide variety of malignancies and may be useful in following fetal development during pregnancy.
ISSN	00278424
e-ISSN	10916490
Journal	Proceedings of the National Academy of Sciences of the United States of America
Issue Number	23
Volume Number	82
Language	English
Publisher	National Academy of Sciences
Publisher Date	1985-01-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Neoplasm Proteins Urine Neoplasms Oncogene Proteins, Viral Pregnancy Proto-Oncogene Proteins Antibodies, Monoclonal Immunology Antibody Specificity Electrophoresis, Polyacrylamide Gel Immunosorbent Techniques Molecular Weight Peptide Fragments Chemical Synthesis Research Support, U.S. Gov't, P.H.S. Multidisciplinary
Content Type	Text
Resource Type	Article
Subject	Multidisciplinary

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Anti-peptide antibodies detect oncogene-related proteins in urine.